fuca1
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  • Official Full Name
  • fucosidase, alpha-L- 1, tissue
  • Background
  • The protein encoded by this gene is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. Mutations in this gene are associated with fucosidosis (FUCA1D), which is an autosomal recessive lysosomal storage disease. A pseudogene of this locus is present on chr 2.
  • Synonyms
  • FUCA1; fucosidase, alpha-L- 1, tissue; tissue alpha-L-fucosidase; Alpha L fucosidase I; Alpha L fucoside fucohydrolase; Alpha-L-fucosidase 1; Alpha-L-fucosidase I; Alpha-L-fucoside fucohydrolase 1; FUCA; FUCO_HUMAN; Tissue alpha L fucosidase; OTTHUMP00000003009
Cat.#:FUCA1-2661HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human FUCA1 Protein, MYC/DDK-tagged
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Cat.#:FUCA1-4543HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FUCA1 Protein, GST-tagged
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Cat.#:FUCA1-1217MTag:His-SUMO
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse FUCA1 Protein, His-SUMO-tagged
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Cat.#:FUCA1-471HTag:His
Source (Host):NS0Species:Human
Product nameRecombinant Human Fucosidase, Alpha-L- 1, Tissue, His-tagged
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Cat.#:FUCA1-1134HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human FUCA1
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Cat.#:FUCA1-13031HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FUCA1, GST-tagged
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Cat.#:FUCA1-28956THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human FUCA1
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Cat.#:FUCA1-53HTag:His
Source (Host):Insect cellSpecies:Human
Product nameRecombinant Human FUCA1 protein, His-tagged
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Cat.#:FUCA1-7730HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FUCA1 protein, His & T7-tagged
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Cat.#:FUCA1-8618HTag:FC/His
Source (Host):HEK293Species:Human
Product nameRecombinant Human FUCA1, His tagged
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Cat.#:FUCA1-6081MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse FUCA1 Protein
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Cat.#:Fuca1-7731MTag:His & T8
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Fuca1 protein, His & T8-tagged
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Cat.#:FUCA1-2407RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat FUCA1 Protein
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Cat.#:Fuca1-7732RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Fuca1 protein, His & T7-tagged
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Cat.#:FUCA1-1212HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human FUCA1 cell lysate
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Involved Pathway

FUCA1 involved in several pathways and played different roles in them. We selected most pathways FUCA1 participated on our site, such as Other glycan degradation, Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with FUCA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Other glycan degradation
ENGASE; MAN2B2; HEXB; HEXA; FUCA1.2; HEXDC; GBA2; MAN2B1; FUCA2; NEU4
Lysosome
GNPTAB; ACP2; HEXA; DNASE2; CD164; AP3S2; NAGPA; TPP1; GALC; SORT1

Protein Function

FUCA1 has several biochemical functions, for example, alpha-L-fucosidase activity, fucose binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FUCA1 itself. We selected most functions FUCA1 had, and list some proteins which have the same functions with FUCA1. You can find most of the proteins on our site.
Function
Related Protein
Function alpha-L-fucosidase activity
Related Protein FUCA1.2; FUCA2; FUCA1.1; FUCA1
Function fucose binding
Related Protein FUOM; SELP; FUCA2; FUCA1

Interacting Protein

FUCA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FUCA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FUCA1.
MARK2; USP21; VAV2