fut9
Share
  • Official Full Name
  • FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) [ Homo sapiens ]
  • Background
  • The protein encoded by this gene belongs to the glycosyltransferase family. It is localized to the golgi, and catalyzes the last step in the biosynthesis of Lewis X (LeX) antigen, the addition of a fucose to precursor polysaccharides. This protein is one of the few fucosyltransferases that synthesizes the LeX oligosaccharide (CD15) expressed in the organ buds progressing in mesenchyma during embryogenesis. It is also responsible for the expression of CD15 in mature granulocytes. A common haplotype of this gene has also been associated with susceptibility to placental malaria infection.
  • Synonyms
  • Fut9; mFUT9; AI746471; AU067636; mFuc-TIX; alpha-(1,3)-fucosyltransferase 9; fuc-TIX; fucT-IX; fucosyltransferase IX; galactoside 3-L-fucosyltransferase
Cat.#:FUT9-4569HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FUT9 Protein, GST-tagged
+Inquiry
Cat.#:FUT9-13048HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FUT9, GST-tagged
+Inquiry
Cat.#:FUT9-219HTag:
Source (Host):CHOSpecies:Human
Product nameRecombinant Human FUT9 protein
+Inquiry
Cat.#:FUT9-26HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human FUT9, His-tagged
+Inquiry
Cat.#:Fut9-3291MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse Fut9, His-tagged
+Inquiry
Cat.#:FUT9-6096MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse FUT9 Protein
+Inquiry
Cat.#:FUT9-2416RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat FUT9 Protein
+Inquiry
Cat.#:FUT9-1770RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey FUT9 Protein, His-tagged
+Inquiry
Cat.#:FUT9-3541CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken FUT9
+Inquiry
Cat.#:FUT9-6111HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human FUT9 293 Cell Lysate
+Inquiry

Involved Pathway

FUT9 involved in several pathways and played different roles in them. We selected most pathways FUT9 participated on our site, such as Glycosphingolipid biosynthesis - globo series, Glycosphingolipid biosynthesis - lacto and neolacto series, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with FUT9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycosphingolipid biosynthesis - globo series
FUT2; ST3GAL2; HEXB; NAGA; ST3GAL1; GLA; FUT9; A4GALT; GBGT1; B3GALT5
Glycosphingolipid biosynthesis - lacto and neolacto series
FUT9; FUT3; B4GALT2; FUT2; ST3GAL3; B3GNT5A; B3GNT4; FUT9A; ABO; B4GALT3
Metabolic pathways
SRM; MCAT; ETNK2; ATP6V1D; HMGCRB; PCYT1BA; NADK2; CYP2B6; ADKA; IMPA2
Other types of O-glycan biosynthesis
ST6GAL2A; B3GALTL; CHST10; EOGT; FUT9A; POMT1; B3GAT1A; GXYLT1B; COLGALT2; PLOD3
terminal O-glycans residues modification
FUT9; GCNT3

Protein Function

FUT9 has several biochemical functions, for example, alpha-(1->3)-fucosyltransferase activity, fucosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FUT9 itself. We selected most functions FUT9 had, and list some proteins which have the same functions with FUT9. You can find most of the proteins on our site.
Function
Related Protein
Function alpha-(1->3)-fucosyltransferase activity
Related Protein FUT11; FUT7; POC1BL; DPY19L4; GTDC2; DPY19L1; POMGNT2; B3GNT9-PS; PIGB; FUT10
Function fucosyltransferase activity
Related Protein B3GNT9-PS; GALNT18A; GTDC2; FUT7; FUT3; GLT8D1; FUT4; UGGT1; DPY19L1; POMGNT2

Interacting Protein

FUT9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FUT9 here. Most of them are supplied by our site. Hope this information will be useful for your research of FUT9.
ZDHHC17; TSSK3

FUT9 Related Articles

Itokazu, Y; Yu, RK; et al. Amyloid beta-Peptide 1-42 Modulates the Proliferation of Mouse Neural Stem Cells: Upregulation of Fucosyltransferase IX and Notch Signaling. MOLECULAR NEUROBIOLOGY 50:186-196(2014).
Li, J; Yang, J; et al. Efficient Generalized Least Squares Method for Mixed Population and Family-based Samples in Genome-wide Association Studies. GENETIC EPIDEMIOLOGY 38:430-438(2014).