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FUT9

  • Official Full Name

    FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) [ Homo sapiens ]

  • Overview

    The protein encoded by this gene belongs to the glycosyltransferase family. It is localized to the golgi, and catalyzes the last step in the biosynthesis of Lewis X (LeX) antigen, the addition of a fucose to precursor polysaccharides. This protein is one of the few fucosyltransferases that synthesizes the LeX oligosaccharide (CD15) expressed in the organ buds progressing in mesenchyma during embryogenesis. It is also responsible for the expression of CD15 in mature granulocytes. A common haplotype of this gene has also been associated with susceptibility to placental malaria infection.
  • Synonyms

    Fut9; mFUT9; AI746471; AU067636; mFuc-TIX; alpha-(1,3)-fucosyltransferase 9; fuc-TIX; fucT-IX; fucosyltransferase IX; galactoside 3-L-fucosyltransferase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rhesus Macaque
  • CHO
  • E.coli
  • E.coli expression system
  • E.Coli or Yeast
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
  • 6×His, GFP
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FUT9-219H Active Recombinant Human FUT9 protein CHO N/A
Human FUT9-26H Recombinant Human FUT9, His-tagged HEK293 His
Human FUT9-13048H Recombinant Human FUT9, GST-tagged E.coli GST 32-359a.a.
Human FUT9-6111HCL Recombinant Human FUT9 293 Cell Lysate HEK293 N/A
Human FUT9-5233HF Recombinant Full Length Human FUT9 Protein, GST-tagged In Vitro Cell Free System GST 359 amino acids
Human FUT9-4569H Recombinant Human FUT9 Protein, GST-tagged Wheat Germ GST
Human FUT9-30H Recombinant Human FUT9 Protein (AA 39-359), N-6×His/GFP tagged HEK293 N-6×His, GFP AA 39-359
Mouse Fut9-3291M Recombinant Mouse Fut9, His-tagged E.Coli or Yeast His 359
Mouse FUT9-6096M Recombinant Mouse FUT9 Protein Mammalian Cell His
Mouse FUT9-3395M-B Recombinant Mouse FUT9 Protein Pre-coupled Magnetic Beads HEK293
Mouse FUT9-3395M Recombinant Mouse FUT9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat FUT9-2416R Recombinant Rat FUT9 Protein Mammalian Cell His
Rat FUT9-2072R Recombinant Rat FUT9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat FUT9-2072R-B Recombinant Rat FUT9 Protein Pre-coupled Magnetic Beads HEK293
Mus musculus (Mouse) RFL11840MF Recombinant Full Length Mouse Alpha-(1,3)-Fucosyltransferase(Fut9) Protein, His-Tagged E.coli expression system His Full Length (1-359)
Rhesus Macaque FUT9-1770R Recombinant Rhesus monkey FUT9 Protein, His-tagged Mammalian Cell His
Rhesus Macaque FUT9-1591R-B Recombinant Rhesus Macaque FUT9 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque FUT9-1591R Recombinant Rhesus Macaque FUT9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken FUT9-3541C Recombinant Chicken FUT9 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FUT9 Related Articles

FUT9 involved in several pathways and played different roles in them. We selected most pathways FUT9 participated on our site, such as Glycosphingolipid biosynthesis - globo series, Glycosphingolipid biosynthesis - lacto and neolacto series, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with FUT9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycosphingolipid biosynthesis - globo seriesFUT2;ST3GAL1;GBGT1L4;FUT9A;B3GALT5;B3GALNT1;GLA;FUT1;NAGA
Glycosphingolipid biosynthesis - lacto and neolacto seriesST3GAL3B;B3GNT1;ST3GAL6;B3GNT5B;FUT3;B3GALT2;B4GALT3;FUT9A;B4GALT2
Metabolic pathwaysPGM1;MGAT1;POLR2J;ITPK1A;ENO1A;CBR2;ALAS1;HYAL3;CDS1
Other types of O-glycan biosynthesisST6GAL2A;GXYLT1B;ST3GAL3;FUT4;ST6GAL1;C3orf64;ST3GAL3B;FUT9;B4GALT3
terminal O-glycans residues modificationFUT9;GCNT3

FUT9 has several biochemical functions, for example, alpha-(1->3)-fucosyltransferase activity, fucosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by FUT9 itself. We selected most functions FUT9 had, and list some proteins which have the same functions with FUT9. You can find most of the proteins on our site.

Function Related Protein
alpha-(1->3)-fucosyltransferase activityFUT3;UGGT1;B3GNT9-PS;GLT8D1;B3GNT9;B3GNT8;PIGB;DPY19L4;FUT6
fucosyltransferase activityFUT1;DPY19L1;PIGB;FUT6;POC1BL;B3GNT9-PS;FUT9B;DPY19L4;FUT3

FUT9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FUT9 here. Most of them are supplied by our site. Hope this information will be useful for your research of FUT9.

ZDHHC17; TSSK3

Itokazu, Y; Yu, RK; et al. Amyloid beta-Peptide 1-42 Modulates the Proliferation of Mouse Neural Stem Cells: Upregulation of Fucosyltransferase IX and Notch Signaling. MOLECULAR NEUROBIOLOGY 50:186-196(2014).
Li, J; Yang, J; et al. Efficient Generalized Least Squares Method for Mixed Population and Family-based Samples in Genome-wide Association Studies. GENETIC EPIDEMIOLOGY 38:430-438(2014).
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