fuz
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  • Official Full Name
  • fuzzy homolog
  • Synonyms
  • FUZ; fuzzy homolog (Drosophila); protein fuzzy homolog; FLJ22688; Fy
Cat.#:FUZ-4571HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FUZ Protein, GST-tagged
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Cat.#:FUZ-2417RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat FUZ Protein
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Cat.#:FUZ-6110HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human FUZ 293 Cell Lysate
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Involved Pathway

FUZ involved in several pathways and played different roles in them. We selected most pathways FUZ participated on our site, such as DNA Double-Strand Break Repair, DNA Repair, Fanconi Anemia Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FUZ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
DNA Double-Strand Break Repair
RIF1; BRCC3; EME1; PARP1; RBBP8; UBE2V2; TOPBP1; TIMELESS; PPP4CB; EME2
DNA Repair
RAD9; BRCC3; USP43; UIMC1; TP53BP1; ACTR5; UBE2L6; RAD9B; RAD18; BARD1
Fanconi Anemia Pathway
FUZ; FAN1; HER9; HES1; BRCA2; APITD1; FANCL; ZBTB32; POLK; RAD51
HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA)
TIMELESS; UIMC1; PPP4R2B; HUS1; RAD1; RHNO1; EME2; GEN1; BABAM1; TIPIN
HDR through Homologous Recombination (HRR)
EME1; RTEL1; RAD9; WRN; RAD9B; RBBP8; FUZ; RAD51AP1; KIAA0146; EME2
Homologous recombination
RAD51; XRCC2; NBN; BLM; RAD54B; RPA2; MUS81; BRCA2; POLD2; XRCC3
Homology Directed Repair
RNF4; PPP4R2B; RTEL1; TOPBP1; TIPIN; EME2; PPP4R2; WRN; FUZ; RHNO1

Protein Function

FUZ has several biochemical functions, for example, 3-flap endonuclease activity, DNA binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FUZ itself. We selected most functions FUZ had, and list some proteins which have the same functions with FUZ. You can find most of the proteins on our site.
Function
Related Protein
Function 3-flap endonuclease activity
Related Protein MUS81; FUZ
Function DNA binding
Related Protein ZFP687; RIMKLB; MIER1; PAX1A; ELF2B; LTF; CLOCKA; SP140L; NKX2.5; AEBP1
Function metal ion binding
Related Protein Itgam&Itgb2; ALOX8; PLAG1; ME2; ZFP451; LMO7A; ESCO2; NUBP1; ZNF567; SLC25A25A
Function protein binding
Related Protein AGTRAP; TFF1; HBP1; METTL1; LYN; TMPRSS4; ERP27; KLK4; CXXC5; PPP1R2P3

Interacting Protein

FUZ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FUZ here. Most of them are supplied by our site. Hope this information will be useful for your research of FUZ.
RSG1

FUZ Related Articles

Brooks, ER; Wallingford, JB; et al. Multiciliated Cells. CURRENT BIOLOGY 24:R973-R982(2014).
Tabler, JM; Barrell, WB; et al. Fuz mutant mice reveal shared mechanisms between ciliopathies and FGF related syndromes. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164A:1888-1888(2014).