FABP5
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Official Full Name
fatty acid binding protein 5 (psoriasis-associated)
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Overview
The fatty-acid-binding proteins (FABPs) are a family of carrier proteins for fatty acids and other lipophilic substances such as eicosanoids and retinoids. These proteins are thought to facilitate the transfer of fatty acids between extra- and intracellular membranes Some family members are also believed to transport lipophilic molecules from outer cell membrane to certain intracellular receptors such as PPAR. Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus. -
Synonyms
FABP5; fatty acid binding protein 5 (psoriasis-associated); EFABP; E-FABP; PAFABP; PA-FABP; fatty acid-binding protein, epidermal; OTTHUMP00000166021; OTTHUMP00000166022; epidermal-type fatty acid-binding protein; psoriasis-associated fatty acid-binding protein homolog; Keratinocyte lipid binding protein; DA11; Cutaneous fatty acid binding protein; CFABP; Fatty acid-binding protein 5; atty acid-binding protein;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Pig
- Rat
- Rhesus Macaque
- E. coli
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mamanlian cells
- Mammalian Cell
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- His|T7
- Myc
- DDK
- MYC
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- FABP5 Related Research Area
FABP5 involved in several pathways and played different roles in them. We selected most pathways FABP5 participated on our site, such as PPAR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FABP5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| PPAR signaling pathway | ANGPTL4;ACOX1;SCD5;PLTP;RXRGA;ACSL4B;ACADL;ACSL3A;ACSL1 |
FABP5 has several biochemical functions, for example, fatty acid binding, lipid binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FABP5 itself. We selected most functions FABP5 had, and list some proteins which have the same functions with FABP5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| fatty acid binding | HNF4A;FABP10A;FABP1;CYP4A14;FABP7A;O3far1;FABP1A;LBFABP;APOC1 |
| lipid binding | APOL3;ACBD6;TRIP10;FABP11B;FNBP1;APOA4B.1;ACOT11;SH3GLB1;APOL4 |
| protein binding | ADRB1;ARL3;PBX1;GEMIN6;PRKRIP1;JAK1;PCTP;ARHGEF1;CTNNA1 |
| transporter activity | STEAP1;SLCO1F4;SLC22A17;OSTB;ABCA6;MFSD10;CRABP1A;PTGDSB;STEAP2 |
FABP5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FABP5 here. Most of them are supplied by our site. Hope this information will be useful for your research of FABP5.
AURKA; RIPK2; EIF1B; GH1; EPB41; HNF1A; MCC; CDK2; VHL; IKBKE; ATG5; PRKAB1; TRAF6; EGFR; SLX4
- Q&As
- Reviews
Q&As (7)
Ask a questionDysregulation or abnormal expression of FABP5 is associated with conditions such as cancer, metabolic disorders, and inflammatory diseases.
Fatty Acid-Binding Protein 5 (FABP5) functions in cellular processes, primarily playing a role in lipid metabolism and fatty acid transport.
FABP5 contributes to the regulation of lipid homeostasis and inflammatory responses in cells, linking lipid metabolism to immune function.
There are potential therapeutic implications related to FABP5 in diseases involving lipid metabolism and inflammation, making it a target for drug development.
FABP5 participates in the binding and transport of fatty acids within cells, facilitating their intracellular trafficking.
FABP5 is predominantly localized in the cytoplasm of cells, where it binds and transports fatty acids.
FABP5 preferentially interacts with long-chain fatty acids, influencing its cellular functions related to lipid metabolism.
Customer Reviews (3)
Write a reviewThe product's rapid action in triggering cellular responses significantly expedited our experiments.
Precise immunoprecipitation results consistently reflected the product's quality.
Replicating outcomes across diverse cell lines underscored the product's consistent behavior.
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