FGF23
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Official Full Name
fibroblast growth factor 23
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Overview
This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013] -
Synonyms
FGF23; fibroblast growth factor 23; ADHR; FGFN; HYPF; HPDR2; PHPTC; phosphatonin; tumor-derived hypophosphatemia inducing factor;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E. coli
- E.coli
- HEK293
- HEK293T
- Human
- Human Cell
- In Vitro Cell Free System
- Insect Cell
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Yeast
- C
- His
- Fc
- Flag
- GST
- His (Fc)
- Avi
- His(C
- ter)
- His|T7
- Myc
- DDK
- N/A
- N
- No tag
- FGF23 Related Articles
- FGF23 Related Research Area
- FGF23 Related Signal Pathway
FGF23 involved in several pathways and played different roles in them. We selected most pathways FGF23 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF23 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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FGF23 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by FGF23 itself. We selected most functions FGF23 had, and list some proteins which have the same functions with FGF23. You can find most of the proteins on our site.
Function | Related Protein |
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FGF23 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF23 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF23.
- Q&As
- Reviews
Q&As (7)
Ask a questionFGF23 levels are elevated in chronic kidney disease, contributing to mineral imbalance.
High FGF23 levels are associated with increased cardiovascular risk.
It decreases renal phosphate reabsorption and 1,25-dihydroxyvitamin D production.
Mutations in FGF23 or related proteins can lead to dysregulated phosphate metabolism.
Strategies include phosphate binders and FGF23 antibodies to manage elevated FGF23 levels.
FGF23 is primarily produced in bone.
FGF23 regulates phosphate and vitamin D metabolism.
Customer Reviews (3)
Write a reviewExcellent results, high purity.
Reliable and effective product.
Quick delivery, product works.
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