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FST

  • Official Full Name

    follistatin

  • Overview

    Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. [provided by RefSeq, Jul 2008]
  • Synonyms

    FST; follistatin; FS; activin-binding protein; follistatin isoform FST317;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • CHO
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Nicotiana Benthamiana
  • Sf21 Insect Cell
  • Spodoptera Frugiperda
  • Wheat Germ
  • Fc
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FST-242H Active Recombinant Human FST Protein, His-tagged HEK293 His
Human FST-152H Active Recombinant Human FST, His-tagged HEK293 His
Human FST-611H Recombinant Human FST protein E.coli N/A 288
Human FST-029H Recombinant Human FST Protein, His-tagged HEK293 His
Human FST-6937H Active Recombinant Human FST protein, His-tagged HEK293 His Met1-Asn317
Human FST-27459TH Recombinant Human FST, His-tagged E.coli His 315 amino acids
Human FST-1617H Recombinant Human Follistatin Sf21 Insect Cell N/A
Human FST-570H Recombinant Human FST Protein, His-tagged E.coli His Arg35~Val283
Human FST-28106TH Recombinant Human FST E.coli N/A
Human FST-3848H Recombinant Human FST, Fc tagged Human Cell Fc
Human FST-1551H Recombinant human FST, Active Nicotiana Benthamiana N/A
Human FST-1833HCL Recombinant Human FST cell lysate Human Cell N/A
Human FST-2557H Recombinant Human FST Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human FST-4524H Recombinant Human FST Protein, GST-tagged Wheat Germ GST
Human FST-2667H Recombinant Human FST Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human FST-5092HF Recombinant Full Length Human FST Protein, GST-tagged In Vitro Cell Free System GST 344 amino acids
Human FST-01H Recombinant Human FST Protein, His-Tagged Insect Cell His 295aa
Human FST-581H Recombinant Human FST Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human FST-167H Recombinant Human FST Protein, His-tagged Human Cell His
Human FST-101H Active Recombinant Human FST Protein E.coli
Mouse Fst-560M Active Recombinant Mouse Follistatin Spodoptera Frugiperda N/A
Mouse Fst-8663M Recombinant Mouse Fst, Fc tagged CHO His
Mouse Fst-6938M Active Recombinant Mouse Fst protein, His-tagged HEK293 His Met1-Trp344
Mouse FST-1771MCL Recombinant Mouse FST cell lysate Human Cell N/A
Mouse FST-001MCL Recombinant Mouse FST cell lysate CHO N/A
Mouse Fst-3092M Recombinant Mouse Fst Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse FST-102M Recombinant Mouse FST Protein E.coli
Rat FST-2398R Recombinant Rat FST Protein Mammalian Cell His
Rat FST-2054R Recombinant Rat FST Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Fst-2759R Recombinant Rat Fst Protein, His-tagged E.coli N-His Arg35-Val283
Rat FST-2054R-B Recombinant Rat FST Protein Pre-coupled Magnetic Beads HEK293
Chicken FST-6754C Recombinant Chicken FST Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FST Related Articles
  • FST Related Research Area

FST involved in several pathways and played different roles in them. We selected most pathways FST participated on our site, such as Antagonism of Activin by Follistatin, BMP receptor signaling, Integrated Pancreatic Cancer Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FST were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Antagonism of Activin by FollistatinFSTL3;FSTB;FST;INHBAA
BMP receptor signalingFST;RGMB;CTDSP2;GREM1;SKI;CALML4;RGMA;HFE2;AHSG
Integrated Pancreatic Cancer PathwayTOP1;FST;DAXX;BRF1;TFF1;JUND;RB1CC1;WRN;MST1
Signal TransductionMYO9B;SPOP;CDC73;NOXO1;GPR18;RDH7;TAS2R16;GPR132;FGD4
Signaling by ActivinINHBAA;FSTL3;FOXH1;DRAP1;FST;FSTB;ACVR1C
TGF Beta Signaling PathwayZFP423;FST;LEFTY1;ZNF423;FOXH1;RUNX3;TGFBR3;ENG;NOG
TGF-beta signaling pathwayINHBB;FSTA;NODAL;ACVR1L;PITX2;LFT1;INHBAB;SMAD5;SMAD7

FST has several biochemical functions, for example, activin binding, heparan sulfate proteoglycan binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FST itself. We selected most functions FST had, and list some proteins which have the same functions with FST. You can find most of the proteins on our site.

Function Related Protein
activin bindingACVR2B;ENG;TGFBR3;FKBP1A;SMAD7;FSTL3;ACVRL1;FST;SMURF1
heparan sulfate proteoglycan bindingGPC1A;GPC5A;AGRN;UBE4A;PLA2G2D;Itgam&Itgb2;GPC6A;AZU1;Gpc2
protein bindingAPOA1;UBR4;RASL10B;SMN2;NKG7;SSX1;SF3B2;PAGE5;CYFIP2
signal transducer activityDRD2A;GHRHRA;TAS2R200.1;OLFR998;GNRHR3;RASGRP3;NDFIP1;GNGT2A;OLFR186

FST has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FST here. Most of them are supplied by our site. Hope this information will be useful for your research of FST.

ANG; DIP2A; Mstn; ADAM12; ADAM8; FSTL1; TK1; MEST; C8orf33

Chen, FF; Ren, P; et al. Follistatin Is a Novel Biomarker for Lung Adenocarcinoma in Humans. PLOS ONE 9:-(2014).
Gokmen-Polar, Y; Goswami, CP; et al. Gene Expression Analysis Reveals Distinct Pathways of Resistance to Bevacizumab in Xenograft Models of Human ER-Positive Breast Cancer. JOURNAL OF CANCER 5:633-645(2014).
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