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GABPB1

Official Full Name

GA binding protein transcription factor, beta subunit 1
Overview

This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex;with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in;activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a;similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding;distinct isoforms have been identified for this gene.
Synonyms

GABPB1; GA binding protein transcription factor, beta subunit 1; GA binding protein transcription factor, beta subunit 2 , GABPB2; GA-binding protein subunit beta-1; E4TF1 47; GABPB; BABPB2; E4TF1; E4TF1-47; E4TF1-53; E4TF1B; GA binding protein transcription factor, beta subunit 2; GABP subunit beta-1; GABP subunit beta-2; GABP1_HUMAN; GABPB-1; GABPB-2; GABPB2; NRF2B1; NRF2B2; Nuclear respiratory factor 2; Transcription factor E4TF1-47; Transcription factor E4TF1-53;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Rhesus Macaque
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Sf9-Baculovirus.
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GABPB1-5260H	Recombinant Full Length Human GABPB1 Protein (1-395), GST-tagged	Sf9-Baculovirus.	GST	1-395 (Full Length)	Inquiry
Human	GABPB1-27461TH	Recombinant Human GABPB1	Wheat Germ	N/A	87 amino acids	Inquiry
Human	GABPB1-50H	Recombinant Human GABPB1 protein, His-tagged	E.coli	His	363aa(including fusion tag)	Inquiry
Human	GABPB1-6068HCL	Recombinant Human GABPB1 293 Cell Lysate	HEK293	N/A		Inquiry
Human	GABPB1-05H	Recombinant Human GABPB1 Protein, N-His-tagged	E.coli	N-His		Inquiry
Human	GABPB1-4633H	Recombinant Human GABPB1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GABPB1-5180HF	Recombinant Full Length Human GABPB1 Protein, GST-tagged	In Vitro Cell Free System	GST	395 amino acids	Inquiry
Human	GABPB1-001H	Recombinant Human GABPB1 Protein, His-tagged	E.coli	His	1-395	Inquiry
Human	GABPB1-06H	Recombinant Human GABPB1 Protein, N-His-tagged	E.coli	N-His		Inquiry
Rhesus Macaque	GABPB1-1791R	Recombinant Rhesus monkey GABPB1 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	GABPB1-1612R	Recombinant Rhesus Macaque GABPB1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	GABPB1-1612R-B	Recombinant Rhesus Macaque GABPB1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	GABPB1-4729Z	Recombinant Zebrafish GABPB1	Mammalian Cell	His		Inquiry
Chicken	GABPB1-1258C	Recombinant Chicken GABPB1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

GABPB1 involved in several pathways and played different roles in them. We selected most pathways GABPB1 participated on our site, such as Mitochondrial biogenesis, Myometrial Relaxation and Contraction Pathways, Organelle biogenesis and maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with GABPB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Mitochondrial biogenesis	TFB2M;TFB1M;MTERF;POLG2;C10orf2;PPARGC1B;PPRC1;GABPB1;ESRRA
Myometrial Relaxation and Contraction Pathways	MAFF;GABPA;CRHR1;RGS18;RGS14;PKIB;ATF5;IGFBP2;GABPB1
Organelle biogenesis and maintenance	ARL13B;IFT43;BBS2;FLR;MRPL50;POLRMT;NPHP3;TTC30A2;CLUAP1
Transcriptional activation of mitochondrial biogenesis	TFB1M;GABPA;C10orf2;MTERF;POLG2;POLRMT;GABPB1;PPRC1

GABPB1 has several biochemical functions, for example, protein binding, protein heterodimerization activity, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GABPB1 itself. We selected most functions GABPB1 had, and list some proteins which have the same functions with GABPB1. You can find most of the proteins on our site.

Function	Related Protein
protein binding	P4HA2;KRT40;TGOLN2;AKT3;TLE3;PIM3;EEF2;GK;RCAN3
protein heterodimerization activity	BDKRB2;GABPB2;GCLC;CYBB;ATF2;TENM3;CAPN2;HER5;PRMT5
transcription factor activity, sequence-specific DNA binding	GLI3;ZFP639;ZNF691;TRP53;VDRB;MECP2;FOXO6;ZNF23;TWIST2
transcription regulatory region DNA binding	MEF2C;KLF17;PRDM5;NR1D1;TP53;PAX2;ZFP746;SOX2;FOS

GABPB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GABPB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GABPB1.

LMO1; TRAF2; TDRD7; MAGEB18; Adgrb2; SNRPB2