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GABRA3

  • Official Full Name

    gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3

  • Overview

    GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are;ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as;benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been;identified.
  • Synonyms

    GABRA3; gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3; gamma-aminobutyric acid receptor subunit alpha-3; GABA(A) receptor subunit alpha 3; GABR A3; GABRA 3; Gamma aminobutyric acid (GABA) A receptor alpha 3; Gamma aminobutyric acid A receptor alpha 3; Gamma aminobutyric acid receptor subunit alpha 3; MGC33793; OTTMUSP00000019432; OTTMUSP00000019433; GABA(A) receptor subunit alpha-3; Gabra-3;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GABRA3-444H Recombinant Human GABRA3 Mammalian Cell His
Human GABRA3-13093H Recombinant Human GABRA3, GST-tagged E.coli GST 24-282a.a.
Human GABRA3-6065HCL Recombinant Human GABRA3 293 Cell Lysate HEK293 N/A
Human GABRA3-4637H Recombinant Human GABRA3 Protein, GST-tagged Wheat Germ GST
Human GABRA3-5187HF Recombinant Full Length Human GABRA3 Protein, GST-tagged In Vitro Cell Free System GST 30-492 amino acids
Human GABRA3-1543H Recombinant Human GABRA3 Protein, His-tagged E.coli N-His Gly30-Gly276
Human GABRA3-2994H Recombinant Human GABRA3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human GABRA3-2994H-B Recombinant Human GABRA3 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GABRA3 Related Articles
  • GABRA3 Related Research Area

GABRA3 involved in several pathways and played different roles in them. We selected most pathways GABRA3 participated on our site, such as Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with GABRA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuroactive ligand-receptor interactionGRIK1;PTGER1B;TAAR12I;PTGER1A;S1PR4;TAAR10C;MCHR2;PRL2;TAAR12G
Retrograde endocannabinoid signalingGNB1;Adcy4;GNGT1;GNAI1;GABRB3;SLC17A6;PLCB2;GNG5;MAPK11
GABAergic synapseGABRR2;GNG5;NSF;GABRQ;SLC12A5;GNGT1;GNG12;GABBR1;GNG11
Nicotine addictionGABRB2;SLC17A7;SLC17A8;GRIN1;GABRA4;GABRG3;GABRA5;GRIN3A;GRIN2A

GABRA3 has several biochemical functions, for example, contributes_to GABA-A receptor activity, benzodiazepine receptor activity, chloride channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GABRA3 itself. We selected most functions GABRA3 had, and list some proteins which have the same functions with GABRA3. You can find most of the proteins on our site.

Function Related Protein
contributes_to GABA-A receptor activityGABRR3A;GABRA3;GABRG1;GABRG2;GABRA5;GABRR2A;GABRQ;GABRA6A;GABRG3
benzodiazepine receptor activityGABRA6;GABRA4;TSPO;GABRA2;GABRA3;GABRG2
chloride channel activityCLCA3;GABRG2;GABRA4;CLCA1;GABRA1;GABRR3;SLC26A6L;BEST1;SLC26A9
inhibitory extracellular ligand-gated ion channel activityGABRA5;GABRA2;GABRA3;GABRA6;GABRE;GABRA1;GABRG1;GABRA4;GABRG3

GABRA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GABRA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GABRA3.

PIK3R1; UGT2B7; SDCBP2

Kawasaki, K; Kondoh, E; et al. Reliable pre-eclampsia pathways based on multiple independent microarray data sets. MOLECULAR HUMAN REPRODUCTION 21:217-224(2015).
Loriot, A; Van Tongelen, A; et al. A novel cancer-germline transcript carrying pro-metastatic miR-105 and TET-targeting miR-767 induced by DNA hypomethylation in tumors. EPIGENETICS 9:1163-1171(2014).
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