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GATM

  • Official Full Name

    glycine amidinotransferase (L-arginine:glycine amidinotransferase)

  • Overview

    This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.
  • Synonyms

    GATM; glycine amidinotransferase (L-arginine:glycine amidinotransferase); glycine amidinotransferase, mitochondrial; AGAT; mitochondrial; AT; GATM_HUMAN; Glycine amidinotransferase; L-arginine:glycine amidinotransferase; Transamidinase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GATM-13171H Recombinant Human GATM, His-tagged E.coli His C-term-350a.a.
Human GATM-28986TH Recombinant Human GATM Wheat Germ N/A 100 amino acids
Human GATM-1925H Recombinant Human GATM protein, His-tagged E.coli His 410
Human GATM-6005HCL Recombinant Human GATM 293 Cell Lysate HEK293 N/A
Human GATM-5393H Recombinant Human GATM Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human GATM-4761H Recombinant Human GATM Protein, GST-tagged Wheat Germ GST
Human GATM-5480HF Recombinant Full Length Human GATM Protein, GST-tagged In Vitro Cell Free System GST 423 amino acids
Human GATM-965H-B Recombinant Human GATM Protein Pre-coupled Magnetic Beads HEK293
Human GATM-833HFL Recombinant Full Length Human GATM Protein, C-Flag-tagged Mammalian cells Flag
Human GATM-965H Recombinant Human GATM Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GATM-6232M Recombinant Mouse GATM Protein Mammalian Cell His
Mouse Gatm-3164M Recombinant Mouse Gatm Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse GATM-3489M Recombinant Mouse GATM Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GATM-3489M-B Recombinant Mouse GATM Protein Pre-coupled Magnetic Beads HEK293
Rat GATM-2485R Recombinant Rat GATM Protein Mammalian Cell His
Rat GATM-2141R-B Recombinant Rat GATM Protein Pre-coupled Magnetic Beads HEK293
Rat GATM-2141R Recombinant Rat GATM Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey GATM-538C Recombinant Cynomolgus GATM Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey GATM-283C-B Recombinant Cynomolgus Monkey GATM Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey GATM-283C Recombinant Cynomolgus Monkey GATM Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish GATM-9937Z Recombinant Zebrafish GATM Mammalian Cell His
Chicken GATM-6310C Recombinant Chicken GATM Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GATM Related Articles

GATM involved in several pathways and played different roles in them. We selected most pathways GATM participated on our site, such as Glycine, serine and threonine metabolism, Arginine and proline metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GATM were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycine, serine and threonine metabolismAGXT2;CBSA;BPGM;ALAS2;CBSB;AMT;GATM;GCSHB;SHMT2
Arginine and proline metabolismALDH9A1A.1;P4HA1B;AMD1;GATM;P4HA3;PRODH;ARG2;PYCRL;PYCR1B
Metabolic pathwaysMAOB;POLR1A;NNT;ST3GAL2;ACSM4;REV3L;ATP5C1;AMPD3B;MAN1A1

GATM has several biochemical functions, for example, glycine amidinotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GATM itself. We selected most functions GATM had, and list some proteins which have the same functions with GATM. You can find most of the proteins on our site.

Function Related Protein
glycine amidinotransferase activity

GATM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GATM here. Most of them are supplied by our site. Hope this information will be useful for your research of GATM.

Gatm; CYP2E1; ytrB; y2173_bacan; yjhB; aspC; q99ib8-pro_0000045598

Wang, FS; Cao, M; et al. Seasonal variation of CO2 diffusion flux from a large subtropical reservoir in East China. ATMOSPHERIC ENVIRONMENT 103:129-137(2015).
Bunel, A; Jorssen, EP; et al. Individual bovine in vitro embryo production and cumulus cell transcriptomic analysis to distinguish cumulus-oocyte complexes with high or low developmental potential. THERIOGENOLOGY 83:228-237(2015).
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