GCNT3
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Official Full Name
glucosaminyl (N-acetyl) transferase 3, mucin type
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Overview
This gene encodes a member of the N-acetylglucosaminyltransferase family. The encoded protein is a beta-6-N-acetylglucosamine-transferase that catalyzes the formation of core 2 and core 4 O-glycans on mucin-type glycoproteins. -
Synonyms
GCNT3; glucosaminyl (N-acetyl) transferase 3, mucin type; beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3; C2/4GnT; C2GnT M; C2GnT2; hC2GnT-M; C2GnT-mucin type; beta1,6GlcNAc-transferase; beta1,6-N-acetylglucosaminyl;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Homo sapiens (Human)
- Human
- Mouse
- Rat
- Rhesus Macaque
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- GCNT3 Related Articles
GCNT3 involved in several pathways and played different roles in them. We selected most pathways GCNT3 participated on our site, such as Metabolic pathways, Metabolism of proteins, Mucin type O-Glycan biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GCNT3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Metabolic pathways | UQCR11;ADSSL1;NDUFB2;COX5AA;PLCH1;ACSL1B;STT3B;CYP27B1;CYP3A7-CYP3AP1 |
Metabolism of proteins | TIMM44;KLHDC3;NSMCE4A;ADAMTS10;BCS1L;MPDU1A;ST6GALNAC1.2;LMAN2L;HYOU1 |
Mucin type O-Glycan biosynthesis | POC1B-GALNT4;C1GALT1;GALNTL4;GALNT6;B3GNT6;GALNT1;WBSCR17;GALNTL1;GALNT9 |
O-linked glycosylation | ADAMTSL1;ADAMTS5;ADAMTS3;ADAMTS10;MUC15;B3GNT6;SPON2;ST6GALNAC2;SPON1 |
O-linked glycosylation of mucins | GALNT13;GALNT6;GALNTL2;GALNT5;MUC5AC;MUC1;ST6GALNAC2;MUC13;GALNTL5 |
Post-translational protein modification | ST6GALNAC2;PPP6C;NAPAB;MGAT4A;GNE;ARSE;ATPBD4;MAN1A2;ADAMTS3 |
mucin core 1 and core 2 O-glycosylation | GALNTL2;GALNT6;GALNT13;GALNT5;GCNT3 |
terminal O-glycans residues modification | FUT9;GCNT3 |
GCNT3 has several biochemical functions, for example, N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity, acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity, beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GCNT3 itself. We selected most functions GCNT3 had, and list some proteins which have the same functions with GCNT3. You can find most of the proteins on our site.
Function | Related Protein |
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N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity | GCNT2;GCNT4;GCNT3 |
acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity | |
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity | GCNT4A;GCNT4;GCNT3;GCNT1 |
GCNT3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GCNT3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GCNT3.
CASK; SNUPN; DHRSX; RBM18
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