gfi1b
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  • Official Full Name
  • growth factor independent 1B transcription repressor
  • Background
  • GFI1b and its homolog GFI1 are transcriptional repressors and important regulators of erythroid and megakaryocytic development and differentiation (1,2). GFI1b negatively regulates transcription by recruiting chromatin regulatory proteins including CoREST
  • Synonyms
  • GFI1B; growth factor independent 1B transcription repressor; growth factor independent 1B (potential regulator of CDKN1A, translocated in CML); zinc finger protein Gfi-1b; growth factor independent protein 1B; potential regulator of CDKN1A translocated in
Cat.#:GFI1B-4850HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GFI1B Protein, GST-tagged
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Cat.#:GFI1B-6648CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken GFI1B
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Cat.#:GFI1B-8277ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GFI1B
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Cat.#:GFI1B-695HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GFI1B cell lysate
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Protein Function

GFI1B has several biochemical functions, for example, DNA binding, RNA polymerase II transcription factor binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GFI1B itself. We selected most functions GFI1B had, and list some proteins which have the same functions with GFI1B. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein TRP53; KDM5BA; ARNTL1A; POU6F2; TIGD3; RYBPB; MXTX1; CXXC1B; GATA1; NR1D2A
Function RNA polymerase II transcription factor binding
Related Protein CHST13; GATA2A; ZFPM1; ID4; GATA3; MIXL1; ZFPM2; TOX2; TBX20; MKX
Function metal ion binding
Related Protein JAZF1B; COL27A1; TRIM35-39; TRIM30A; ING5B; ZFP74; ZNF710A; ATP1A1A.4; SCNM1-PS; DZIP1
Function protein binding
Related Protein TAC1; CROP; MRC2; KRTAP4-12; PRPF40A; KIAA1609; SMUG1; TIGIT; POLR1D; MAMSTR

Interacting Protein

GFI1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GFI1B here. Most of them are supplied by our site. Hope this information will be useful for your research of GFI1B.
NELL2; CENPJ; JAG2; BEGAIN; AGRN; HGS; KALRN; MEGF6; EFEMP2; CENPB; LAMB1; ACTN1; TRIM27; TAF1

GFI1B Related Articles

Stevenson, WS; Morel-Kopp, MC; et al. Platelets are not all gray in GFI1B disease. CLINICAL GENETICS 87:299-299(2015).
Lee, C; Northcott, PA; et al. REGULATION OF MEDULLOBLASTOMA FORMATION BY Gfi1 AND Gfi1B. NEURO-ONCOLOGY 16:-(2014).