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GFM1

  • Official Full Name

    G elongation factor, mitochondrial 1

  • Overview

    Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known.
  • Synonyms

    GFM1; G elongation factor, mitochondrial 1; G translation elongation factor, mitochondrial; elongation factor G, mitochondrial; EFGM; EGF1; GFM; EF-Gmt; mEF-G 1; elongation factor G1; mitochondrial elongation factor G; mitochondrial elongation factor G1;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GFM1-7826H Recombinant Human GFM1 protein, His & T7-tagged E.coli His/T7 Met1~Val158 (Accession # Q96RP9)
Human GFM1-28742TH Recombinant Human GFM1, His-tagged E.coli His
Human GFM1-977H-B Recombinant Human GFM1 Protein Pre-coupled Magnetic Beads HEK293
Human GFM1-4852H Recombinant Human GFM1 Protein, GST-tagged Wheat Germ GST
Human GFM1-5381HF Recombinant Full Length Human GFM1 Protein, GST-tagged In Vitro Cell Free System GST 751 amino acids
Human GFM1-1770HFL Recombinant Full Length Human GFM1 Protein, C-Flag-tagged Mammalian cells Flag
Human GFM1-977H Recombinant Human GFM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GFM1-6311M Recombinant Mouse GFM1 Protein Mammalian Cell His
Mouse Gfm1-7827M Recombinant Mouse Gfm1 protein, His & T7-tagged E.coli His/T7 Glu511~Asn751 (Accession # Q8K0D5)
Mouse GFM1-3537M-B Recombinant Mouse GFM1 Protein Pre-coupled Magnetic Beads HEK293
Mouse GFM1-3537M Recombinant Mouse GFM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Gfm1-3192M Recombinant Mouse Gfm1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat GFM1-2511R Recombinant Rat GFM1 Protein Mammalian Cell His
Rat GFM1-2167R-B Recombinant Rat GFM1 Protein Pre-coupled Magnetic Beads HEK293
Rat GFM1-2167R Recombinant Rat GFM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque GFM1-1832R Recombinant Rhesus monkey GFM1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque GFM1-1653R Recombinant Rhesus Macaque GFM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque GFM1-1653R-B Recombinant Rhesus Macaque GFM1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish GFM1-4949Z Recombinant Zebrafish GFM1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

GFM1 involved in several pathways and played different roles in them. We selected most pathways GFM1 participated on our site, such as Mitochondrial translation, Mitochondrial translation elongation, Organelle biogenesis and maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with GFM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Mitochondrial translationMRPL49;CHCHD1;MRPS34;MRPS26;PTCD3;MRPL48;MRPL38;MTIF3;MRPS25
Mitochondrial translation elongationMRPS36;TSFM;MRPL28;MRPL50;MRPL41;GADD45GIP1;MRPS28;MRPS24;MRPL44
Organelle biogenesis and maintenanceIFT52;MTRF1L;IQCB1;MRPS23;MTERF;ATAT1;PPRC1;RPGRIP1L;MRPL38

GFM1 has several biochemical functions, for example, GTP binding, GTPase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GFM1 itself. We selected most functions GFM1 had, and list some proteins which have the same functions with GFM1. You can find most of the proteins on our site.

Function Related Protein
GTP bindingSEPT5;DNAJC27;RAB39BB;DRG1;GIMAP8;RP2;ARF1;KRAS;RAB6B
GTPase activityRAB7L1;RAB9B;GNAZ;MTG1;RAB18;RABL2A;EEF1A1L2;RND1;GNA15.4
poly(A) RNA bindingAPEH;TOP1;MRPL42;RBM14;GLTSCR2;RDBP;RARS2;S100A4;AATF
protein bindingKIAA0368;ENC1;CCDC53;ZFP143;KCNE2;ERP27;SLC26A3;AKAP7;CIRH1A
translation elongation factor activityEEFSEC;EEF1G;EEF2A.1;EEF1DA;EEF1B2;TSFM;TUFM;EIF5A;EEF1A1A

GFM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GFM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GFM1.

TRIM63; TRIM55; q8clv2_yerpe; SMURF2; MAPK13; SLX4; MAGOHB; Dda1

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