gga1
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  • Official Full Name
  • ADP-ribosylation factor binding protein
  • Background
  • This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • GGA1; ADP-ribosylation factor binding protein
Cat.#:GGA1-4865HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GGA1 Protein, GST-tagged
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Cat.#:GGA1-28744THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GGA1, His-tagged
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Cat.#:GGA1-6322MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GGA1 Protein
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Cat.#:GGA1-1199ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GGA1
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Cat.#:GGA1-698HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GGA1 cell lysate
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Involved Pathway

GGA1 involved in several pathways and played different roles in them. We selected most pathways GGA1 participated on our site, such as Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with GGA1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Lysosome
ATP6V0CA; ATP6AP1B; PSAPL1; SGSH; IDUA; CTSH; GNSB; ATP6V0A2; GGA3; ATP6V0A2B

Protein Function

GGA1 has several biochemical functions, for example, molecular_function, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GGA1 itself. We selected most functions GGA1 had, and list some proteins which have the same functions with GGA1. You can find most of the proteins on our site.
Function
Related Protein
Function molecular_function
Related Protein RNFT1; D19WSU162E; ATXN7L2A; PSG2; TMEM54; OLFML3A; TSPAN34; FAM180A; FAM160B1; GM239
Function protein binding
Related Protein HSPA1B; MYO5B; ATP10A; VPREB1; RUFY3; TYROBP; CD5; DAZAP2; C19orf73; CCDC55

Interacting Protein

GGA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GGA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GGA1.
RABEP1; IGF2R; SORT1; RNF11; DTNB