gins1
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  • Official Full Name
  • GINS complex subunit 1 (Psf1 homolog)
  • Background
  • The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1, Psf2 (GINS2; MIM 610609), and;Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in;yeast and Xenopus egg extracts (Ueno et al., 2005 (PubMed 16287864)).
  • Synonyms
  • GINS1; GINS complex subunit 1 (Psf1 homolog); DNA replication complex GINS protein PSF1; KIAA0186; PSF1; GINS complex subunit 1; partner of sld five-1; partner of sld5; PSF1 homolog; RP4-691N24.2
Cat.#:GINS1-4908HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GINS1 Protein, GST-tagged
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Cat.#:GINS1-1973CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken GINS1
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Cat.#:GINS1-1589ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GINS1
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Cat.#:GINS1-5934HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GINS1 293 Cell Lysate
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Involved Pathway

GINS1 involved in several pathways and played different roles in them. We selected most pathways GINS1 participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, DNA Replication, which may be useful for your reference. Also, other proteins which involved in the same pathway with GINS1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell Cycle
MAU2; TUBGCP2; LMNB1; HDAC6; TUBB4B; MDM2; CDK1; TTK; GINS1; PDS5A
Cell Cycle, Mitotic
DSN1; CENPJ; MAU2; CEP290; SKA1; PDS5A; NEK9; CP110; CENPE; CDCA5
DNA Replication
RPA4; FEN1; POLD1; RFC2; POLD2; DNA2; POLE; POLA1; RFC5; MCM6
DNA strand elongation
GINS3; DNA2; GINS1; GINS4; GINS2
S Phase
MYCA; GINS1; GINS2; GINS3; ESCO2; GINS4; ESCO1
Synthesis of DNA
GINS2; GINS3; GINS1; GINS4
Unwinding of DNA
GINS4; GINS1; GINS3; GINS2

Protein Function

GINS1 has several biochemical functions, for example, 3-5 DNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GINS1 itself. We selected most functions GINS1 had, and list some proteins which have the same functions with GINS1. You can find most of the proteins on our site.
Function
Related Protein
Function 3-5 DNA helicase activity
Related Protein ERCC3; FBXO18; CDC45; WRN; GINS1