GJB1
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Official Full Name
gap junction protein, beta 1, 32kDa
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Overview
This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene cause X-linked Charcot-Marie-Tooth disease, an inherited peripheral neuropathy. Alternatively spliced transcript variants encoding the same protein have been found for this gene. -
Synonyms
GJB1; gap junction protein, beta 1, 32kDa; CMTX, CMTX1, gap junction protein, beta 1, 32kD (connexin 32, Charcot Marie Tooth neuropathy, X linked) , gap junction protein, beta 1, 32kDa (connexin 32) , gap junction protein, beta 1, 32kDa (connexin 32, Charcot Marie Tooth neuropathy, X linked); gap junction beta-1 protein; Charcot Marie Tooth neuropathy; X linked; connexin 32; CX32; Charcot Marie Tooth neuropathy X linked; CMTX 1; CMTX; CMTX1; Connexin-32; Connexin32; CX 32; CXB1_HUMAN; GAP junction 28 kDa liver protein; Gap junction beta 1 protein; Gap junction protein beta 1 32kD; Gap junction protein beta 1; Gap junction protein beta-1 32kD; GJB 1; OTTHUMP00000023502; OTTHUMP00000023503; OTTHUMP00000023504;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Bos taurus (Bovine)
- Chicken
- Equus caballus (Horse)
- Homo sapiens (Human)
- Human
- Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- Rhesus Macaque
- Xenopus laevis (African clawed frog)
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Protein Conjugation
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | GJB1-4926H | Recombinant Human GJB1 Protein, GST-tagged | Wheat Germ | GST |
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| Human | GJB1-5293HF | Recombinant Full Length Human GJB1 Protein, GST-tagged | In Vitro Cell Free System | GST | 283 amino acids |
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| Human | GJB1-1579H | Recombinant Human GJB1 Protein, His&GST-tagged | E.coli | N-His&GST | Met1-Thr130 |
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| Human | GJB1-2810H | Recombinant Human GJB1 Protein, His-tagged, OVA Conjugated | Protein Conjugation | N-His | Lys265-Arg279 |
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| Rat | GJB1-2551R | Recombinant Rat GJB1 Protein | Mammalian Cell | His |
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| Rat | GJB1-2207R-B | Recombinant Rat GJB1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | GJB1-2207R | Recombinant Rat GJB1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Bos taurus (Bovine) | RFL762BF | Recombinant Full Length Bovine Gap Junction Beta-1 Protein(Gjb1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-284) |
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| Equus caballus (Horse) | RFL10344EF | Recombinant Full Length Horse Gap Junction Beta-1 Protein(Gjb1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-283) |
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| Homo sapiens (Human) | RFL32297HF | Recombinant Full Length Human Gap Junction Beta-1 Protein(Gjb1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-283) |
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| Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) | RFL19028MF | Recombinant Full Length Macaca Fascicularis Gap Junction Beta-1 Protein(Gjb1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-283) |
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| Mus musculus (Mouse) | RFL2011MF | Recombinant Full Length Mouse Gap Junction Beta-1 Protein(Gjb1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-283) |
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| Rattus norvegicus (Rat) | RFL10059RF | Recombinant Full Length Rat Gap Junction Beta-1 Protein(Gjb1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-283) |
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| Rhesus Macaque | GJB1-1859R | Recombinant Rhesus monkey GJB1 Protein, His-tagged | Mammalian Cell | His |
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| Rhesus Macaque | GJB1-1679R-B | Recombinant Rhesus Macaque GJB1 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rhesus Macaque | GJB1-1679R | Recombinant Rhesus Macaque GJB1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Xenopus laevis (African clawed frog) | RFL3021XF | Recombinant Full Length Xenopus Laevis Gap Junction Beta-1 Protein(Gjb1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-264) |
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| Chicken | GJB1-5941C | Recombinant Chicken GJB1 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
GJB1 involved in several pathways and played different roles in them. We selected most pathways GJB1 participated on our site, such as Calcium Regulation in the Cardiac Cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with GJB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Calcium Regulation in the Cardiac Cell | YWHAQ;CX27.5;RGS14A;ADRa1A;RGS20;KCNJ3;ADRB3;GJC2;GJA5 |
GJB1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by GJB1 itself. We selected most functions GJB1 had, and list some proteins which have the same functions with GJB1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
GJB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GJB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GJB1.
- Q&As
- Reviews
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