GJB4
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Official Full Name
gap junction protein, beta 4, 30.3kDa
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Overview
This gene encodes a transmembrane connexin protein that is a component of gap junctions. Mutations in this gene have been associated with erythrokeratodermia variabilis, progressive symmetric erythrokeratoderma and hearing impairment. -
Synonyms
GJB4; gap junction protein, beta 4, 30.3kDa; gap junction protein, beta 4 , gap junction protein, beta 4 (connexin 30.3); gap junction beta-4 protein; connexin 30.3; CX30.3; Gap junction beta 4 protein; connexin-30.3; OTTHUMP00000004185; EKV;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
GJB4 involved in several pathways and played different roles in them. We selected most pathways GJB4 participated on our site, such as Calcium Regulation in the Cardiac Cell, Gap junction assembly, Gap junction trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with GJB4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Calcium Regulation in the Cardiac Cell | RGS10;RGS14;GNB3B;GJB2;ADRa1A;ADRB3;RGS6;GJB6;ADRA1D |
| Gap junction assembly | CX30.3;GJD3;GJB2;GJB3;GJA4;GJB7;GJC1;CX27.5;GJB4 |
| Gap junction trafficking | GJA5;GJB3;GJD3;GJB4;GJB5;GJC1;CX30.3;GJA8;CX27.5 |
| Gap junction trafficking and regulation | GJD3;GJC1;MYO6A;CX30.3;GJB3;GJB5;GJA5;GJB2;MYO6 |
| Membrane Trafficking | CX30.3;COPE;COPG;GJB5;TFR1B;TMED2;GORASP1;SNX9A;ARCN1A |
| Vesicle-mediated transport | STAB2;SCGB3A2;NAPG;FTH1A;HPX;GJA5;AP3S1;PICALM;CD163 |
GJB4 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by GJB4 itself. We selected most functions GJB4 had, and list some proteins which have the same functions with GJB4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
GJB4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GJB4 here. Most of them are supplied by our site. Hope this information will be useful for your research of GJB4.
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