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GLIPR1

Official Full Name

GLI pathogenesis-related 1
Overview

This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Synonyms

GLIPR1; GLI pathogenesis-related 1; GLI pathogenesis related 1 (glioma); glioma pathogenesis-related protein 1; GliPR; RTVP1; CRISP 7; CRISP7; GLI pathogenesis related 1; GLI pathogenesis-related 1 (glioma); Glioma pathogenesis related protein 1; GLIP1_HUMAN; GliPR 1; Protein RTVP-1; RELATED TO TESTIS SPECIFIC, VESPID, AND PATHOGENESIS PROTEINS 1; RTVP 1; Testes specific vespid and pathogenesis protein 1; testes-specific vespid and pathogenesis protein 1; related to testis-specific, vespid, and pathogenesis proteins 1;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Homo sapiens (Human)
Human
Mouse
Mus musculus (Mouse)
Rhesus Macaque

Source

E.coli
E.coli expression system
HEK293
Human Cell
Mammalian Cell
Mammalian cells
Wheat Germ

Tag

C
His
GST
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GLIPR1-3190H	Recombinant Human GLIPR1, His tagged	Human Cell	His		Inquiry
Human	GLIPR1-2392HCL	Recombinant Human GLIPR1 cell lysate	Human Cell	N/A		Inquiry
Human	GLIPR1-2966H	Recombinant Human GLIPR1 protein, His-tagged	E.coli	His	22-232aa	Inquiry
Human	GLIPR1-4959H	Recombinant Human GLIPR1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GLIPR1-3451H	Recombinant Human GLIPR1 Protein (Asn22-Arg232), C-His tagged	Mammalian cells	C-His	Asn22-Arg232	Inquiry
Mouse	GLIPR1-157M	Recombinant Mouse Glipr1, His tagged	Human Cell	His		Inquiry
Mouse	GLIPR1-807MCL	Recombinant Mouse GLIPR1 cell lysate	Human Cell	N/A		Inquiry
Homo sapiens (Human)	RFL36506HF	Recombinant Full Length Human Glioma Pathogenesis-Related Protein 1(Glipr1) Protein, His-Tagged	E.coli expression system	His	Full Length of Mature Protein (22-266)	Inquiry
Mus musculus (Mouse)	RFL19881MF	Recombinant Full Length Mouse Glioma Pathogenesis-Related Protein 1(Glipr1) Protein, His-Tagged	E.coli expression system	His	Full Length of Mature Protein (18-255)	Inquiry
Rhesus Macaque	GLIPR1-1867R	Recombinant Rhesus monkey GLIPR1 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	GLIPR1-1687R	Recombinant Rhesus Macaque GLIPR1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	GLIPR1-1687R-B	Recombinant Rhesus Macaque GLIPR1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
GLIPR1 Related Articles
GLIPR1 Related Research Area

GLIPR1 involved in several pathways and played different roles in them. We selected most pathways GLIPR1 participated on our site, such as Fatty acid, triacylglycerol, and ketone body metabolism, Metabolism, Metabolism of lipids and lipoproteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with GLIPR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Fatty acid, triacylglycerol, and ketone body metabolism	APOA5;ACOT9.2;GPAT2;DGAT1B;GRHL1;ACOT13;PPARGC1B;MED31;AGPAT2
Metabolism	TIAM2;MED31;APOC2;ECI1;COQ6;MARCKSB;CYP2R1;ADSL;MED20
Metabolism of lipids and lipoproteins	FA2H;ALOX5B.3;ACOT11A;FIG4;DECR1;FABP1B.1;CERS4A;CHKA;SGMS2
PPARA activates gene expression	CDK19;MED8;MED6;PLIN2;MED19;MED7;MED15;G0S2;TIAM2
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	MED19;MED9;MED16;MTF1;CDK19;MED23;MED26;MED20;MED21

GLIPR1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by GLIPR1 itself. We selected most functions GLIPR1 had, and list some proteins which have the same functions with GLIPR1. You can find most of the proteins on our site.

Function	Related Protein

GLIPR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GLIPR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GLIPR1.

queE

Zhang, L; Yang, B; et al. Potential therapeutic mechanism of genistein in breast cancer involves inhibition of cell cycle regulation. MOLECULAR MEDICINE REPORTS 11:1820-1826(2015).

Chakrabarti, S; Multani, S; et al. Whole genome expression profiling in chewing-tobacco-associated oral cancers: a pilot study. MEDICAL ONCOLOGY 32:-(2015).

p53 Pathway