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GLRA2

Official Full Name

glycine receptor, alpha 2
Overview

The glycine receptor consists of two subunits, alpha and beta, and acts as a pentamer. The protein encoded by this gene is an alpha subunit and can bind strychnine. Several transcript variants encoding different isoforms have been found for this gene.
Synonyms

GLRA2; glycine receptor, alpha 2; GLR; glycine receptor subunit alpha-2; GLRA2_HUMAN; Glycine receptor alpha 2 polypeptide; Glycine receptor alpha 2 subunit; Glycine receptor subunit alpha 2; Gycine receptor alpha 2; glycine receptor, alpha-2 polypeptide;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Rat
Rhesus Macaque
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
His|T7
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GLRA2-27147TH	Recombinant Human GLRA2	Wheat Germ	N/A	102 amino acids	Inquiry
Human	GLRA2-295HCL	Recombinant Human GLRA2 lysate	HEK293	N/A		Inquiry
Human	GLRA2-4972H	Recombinant Human GLRA2 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GLRA2-5344HF	Recombinant Full Length Human GLRA2 Protein, GST-tagged	In Vitro Cell Free System	GST	28-452 amino acids	Inquiry
Rat	GLRA2-2568R	Recombinant Rat GLRA2 Protein	Mammalian Cell	His		Inquiry
Rat	Glra2-1366R	Recombinant Rat Glra2 protein, His & T7-tagged	E.coli	His/T7	Lys28~Gln253 (Accession # P22771)	Inquiry
Rat	GLRA2-2223R-B	Recombinant Rat GLRA2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	GLRA2-2223R	Recombinant Rat GLRA2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	GLRA2-1872R	Recombinant Rhesus monkey GLRA2 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	GLRA2-1692R	Recombinant Rhesus Macaque GLRA2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	GLRA2-1692R-B	Recombinant Rhesus Macaque GLRA2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	GLRA2-7630Z	Recombinant Zebrafish GLRA2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

GLRA2 involved in several pathways and played different roles in them. We selected most pathways GLRA2 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GLRA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Neuroactive ligand-receptor interaction	GABRA6;P2RX3B;TAAR12E;MTNR1BB;CHRNE;GRPR;P2RX3A;HTR1F;PTGFR

GLRA2 has several biochemical functions, for example, extracellular-glycine-gated chloride channel activity, glycine binding, transmitter-gated ion channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GLRA2 itself. We selected most functions GLRA2 had, and list some proteins which have the same functions with GLRA2. You can find most of the proteins on our site.

Function	Related Protein
extracellular-glycine-gated chloride channel activity	SIX2A;GLRBB;GLRA4A;GLRBA;GLRB;GLRA2;GLRA1
glycine binding	GNMT;ALAS2;GRIN2B;GLRA4B;GLDC;GLRA2;GLRA1;GRIN3B;GSS
transmitter-gated ion channel activity	GLRA3;SIX2A;GLRA1;GLRA2;GLRA4A;GLRA4B

GLRA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GLRA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GLRA2.

PSD; BAG6; GDI2; SEC23A; GPR108; DDX24