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GMPPB

  • Official Full Name

    GDP-mannose pyrophosphorylase B

  • Overview

    This gene is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, a reaction involved in the production of N-linked oligosaccharides. Alternatively spliced transcript variants encoding distinct isoforms have been described.
  • Synonyms

    GMPPB; GDP-mannose pyrophosphorylase B; mannose-1-phosphate guanyltransferase beta; KIAA1851; mannose-1-phosphate guanylyltransferase; GTP-mannose-1-phosphate guanylyltransferase beta;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GMPPB-13338H Recombinant Human GMPPB, His-tagged E.coli His 1-360a.a.
Human GMPPB-5878HCL Recombinant Human GMPPB 293 Cell Lysate HEK293 N/A
Human GMPPB-5018H Recombinant Human GMPPB Protein, GST-tagged Wheat Germ GST
Human GMPPB-5418HF Recombinant Full Length Human GMPPB Protein, GST-tagged In Vitro Cell Free System GST 360 amino acids
Human GMPPB-6086H Recombinant Human GMPPB Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse GMPPB-7006M Recombinant Mouse GMPPB Protein Mammalian Cell His
Mouse GMPPB-3749M-B Recombinant Mouse GMPPB Protein Pre-coupled Magnetic Beads HEK293
Mouse GMPPB-3749M Recombinant Mouse GMPPB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Gmppb-3250M Recombinant Mouse Gmppb Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque GMPPB-1887R Recombinant Rhesus monkey GMPPB Protein, His-tagged Mammalian Cell His
Rhesus Macaque GMPPB-1707R Recombinant Rhesus Macaque GMPPB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque GMPPB-1707R-B Recombinant Rhesus Macaque GMPPB Protein Pre-coupled Magnetic Beads HEK293
Zebrafish GMPPB-934Z Recombinant Zebrafish GMPPB Mammalian Cell His
Chicken GMPPB-5586C Recombinant Chicken GMPPB Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GMPPB Related Articles

GMPPB involved in several pathways and played different roles in them. We selected most pathways GMPPB participated on our site, such as Fructose and mannose metabolism, Amino sugar and nucleotide sugar metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GMPPB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Fructose and mannose metabolismPFKFB4;TIGARA;AKR1B1L;ALDOC;PFKFB2A;TPI1;FPGT;C12orf5;TPI1B
Amino sugar and nucleotide sugar metabolismHEXB;CHIT1;GFPT1;PGM2;GMPPAB;CHIA.2;NANSA;GALT;GMDS
Metabolic pathwaysNMRK2;PIK3C2G;NDUFA7;NME2;ITGB1BP3;MAOB;ASNS;MIBP;LYCAT

GMPPB has several biochemical functions, for example, GTP binding, mannose-1-phosphate guanylyltransferase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GMPPB itself. We selected most functions GMPPB had, and list some proteins which have the same functions with GMPPB. You can find most of the proteins on our site.

Function Related Protein
GTP bindingRAP2C;RHOD;IIGP1;DNAJC27;RAB7B;GNA15;EEF2A.2;SAR1B;RHOT1B
mannose-1-phosphate guanylyltransferase activityGMPPB;GMPPAA;GMPPAB
protein bindingRTN2;SLC11A2;HARS2;ARL6IP4;GPRASP2;MYL12A;TAF7L;TAL2;RC3H2

GMPPB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GMPPB here. Most of them are supplied by our site. Hope this information will be useful for your research of GMPPB.

GMPPA; TXNDC5; TSC22D1; Sesn2

Bertoli, M; Evangelista, T; et al. Intrafamilial heterogeneity in an alpha-dystroglycanopathy due to GDP-Mannose Pyrophosphorylase B (GMPPB) mutations. NEUROMUSCULAR DISORDERS 24:915-916(2014).
Raphael, AR; Couthouis, J; et al. Congenital muscular dystrophy and generalized epilepsy caused by GMPPB mutations. BRAIN RESEARCH 1575:66-71(2014).
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