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GMPS

  • Official Full Name

    guanine monphosphate synthetase

  • Overview

    In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.
  • Synonyms

    GMPS; guanine monphosphate synthetase; GMP synthase [glutamine-hydrolyzing]; GMP synthase; GMP synthetase; MLL/GMPS fusion protein; glutamine amidotransferase; guanosine 5-monophosphate synthase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GMPS-13341H Recombinant Human GMPS, GST-tagged E.coli GST 345-693a.a.
Human GMPS-1927H Recombinant Human Guanine Monphosphate Synthetase, His-tagged His
Human GMPS-5873HCL Recombinant Human GMPS 293 Cell Lysate HEK293 N/A
Human GMPS-5422HF Recombinant Full Length Human GMPS Protein, GST-tagged In Vitro Cell Free System GST 693 amino acids
Human GMPS-2779H Recombinant Human GMPS protein(11-540 aa), C-His-tagged E. coli C-His 11-540 aa
Human GMPS-3384H Recombinant Human GMPS Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human GMPS-5024H Recombinant Human GMPS Protein, GST-tagged Wheat Germ GST
Human GMPS-2206H Recombinant Human GMPS Protein, His-tagged E.coli N-His Met1-Glu263
Mouse Gmps-3252M Recombinant Mouse Gmps Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat GMPS-2589R Recombinant Rat GMPS Protein Mammalian Cell His
Rat GMPS-2244R-B Recombinant Rat GMPS Protein Pre-coupled Magnetic Beads HEK293
Rat GMPS-2244R Recombinant Rat GMPS Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque GMPS-1888R Recombinant Rhesus monkey GMPS Protein, His-tagged Mammalian Cell His
Rhesus Macaque GMPS-1708R-B Recombinant Rhesus Macaque GMPS Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque GMPS-1708R Recombinant Rhesus Macaque GMPS Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish GMPS-10865Z Recombinant Zebrafish GMPS Mammalian Cell His
Chicken GMPS-1693C Recombinant Chicken GMPS Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GMPS Related Articles

GMPS involved in several pathways and played different roles in them. We selected most pathways GMPS participated on our site, such as Purine metabolism, Drug metabolism - other enzymes, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GMPS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Purine metabolismIMPDH2;GART;ADPRM;POLA2;PDE4D;POLR3GLB;PDE2A;PRIM2;NTPCR
Drug metabolism - other enzymesTYMP;DPYS;ITPA;UCK2;UPB1;UGT1A9;UGT2A1;UGT2A3;UGT2B7
Metabolic pathwaysPNAT3;PLA2G4A;ALDH2;GUK1;GLCEB;NDUFAB1A;ADSS;GALNT4;GART

GMPS has several biochemical functions, for example, ATP binding, GMP synthase (glutamine-hydrolyzing) activity, GMP synthase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GMPS itself. We selected most functions GMPS had, and list some proteins which have the same functions with GMPS. You can find most of the proteins on our site.

Function Related Protein
ATP bindingCSNK1E;PASK;NUAK1;MARK2;ABCB6A;ROCK2A;PAPSS1;STK32A;HSPA4A
GMP synthase (glutamine-hydrolyzing) activity
GMP synthase activity
pyrophosphatase activityPHOSPHO1;GMPS;PRUNE2;ALPL;CANT1B;CANT1A;NUDT19;DOM3Z

GMPS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GMPS here. Most of them are supplied by our site. Hope this information will be useful for your research of GMPS.

USP7; VCAM1; HLA-B; HLA-C; IKBKE; TCEAL1; DDA1; BABAM1; PRKAG2; PRKAB1; AGPAT2; ZNF16; manX; 15-deoxy-delta(12,14; FN1; PAX6

Venable, AS; Williams, RR; et al. An analysis of endothelial microparticles as a function of cell surface antibodies and centrifugation techniques. JOURNAL OF IMMUNOLOGICAL METHODS 406:117-123(2014).
Zhan, WB; Wang, XL; et al. The VP37-binding protein F(1)ATP synthase beta subunit involved in WSSV infection in shrimp Litopenaeus vannamei. FISH & SHELLFISH IMMUNOLOGY 34:228-235(2013).
  • Q&As
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