gng2
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  • Official Full Name
  • Guanine Nucleotide Binding Protein (G Protein), Gamma 2
  • Background
  • Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 is a protein that in humans is encoded by the GNG2 gene.
  • Synonyms
  • GNG2; G gamma-I; guanine nucleotide binding protein (G protein), gamma 2; guanine nucleotide binding protein gamma 2; guanine nucleotide-binding protein G(I)/G(O) gamma-2 subunit; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2; Gγ-2-Subunit; G gamma I; GNG 2
Cat.#:GNG2-5068HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GNG2 Protein, GST-tagged
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Cat.#:GNG2-13363HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GNG2, GST-tagged
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Cat.#:GNG2-7036MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GNG2 Protein
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Cat.#:GNG2-1904RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey GNG2 Protein, His-tagged
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Cat.#:GNG2-3689CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken GNG2
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Cat.#:GNG2-3864ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GNG2
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Cat.#:GNG2-5853HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GNG2 293 Cell Lysate
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Involved Pathway

GNG2 involved in several pathways and played different roles in them. We selected most pathways GNG2 participated on our site, such as Ras signaling pathway, Chemokine signaling pathway, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNG2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ras signaling pathway
RAF1; PLCG1; FGFR4; RAC2; RASAL3; GNG12; FGF2; PAK1; FGF13; Fgf15
Chemokine signaling pathway
CCL6; CCL24; XCR1; CCL16; CCR7; CCL1; CXCL9; BRAF; CXCR5; ARRB2
PIK-Akt signaling pathway
RPTOR; LAMA2; FGF21; THBS1; PPP2R2C; PCK2; CCND3; FGFR3; FGF16; GNG7
Circadian entrainment
CALM1; CACNA1G; RYR3; NOS1AP; KCNJ9; ADCYAP1R1; PLCB2; CAMK2A; GNGT2; RYR1
Retrograde endocannabinoid signaling
ITPR3; PLCB2; RIMS1; GNAI2; MAPK13; GNG7; GABRG1; PLCB3; GRM1; GNG3
Glutamatergic synapse
GRIA1; GNB1; PPP3R1; PLCB1; SLC1A2; GNAQ; SLC1A1; HOMER2; SLC38A1; GNG7
Cholinergic synapse
GNB1; KRAS; CHRNB2; PRKCB; PIK3R5; GNAQ; PIK3CD; PRKCA; GNG12; SLC5A7
Serotonergic synapse
GNG13; HTR1A; PLA2G4C; HTR1F; GNG2; PRKACA; GNG10; PLCB4; ALOX5; BRAF
GABAergic synapse
PLCL1; GNG2; SLC38A1; GABRR2; SRC; GNG7; GNAI1; GNB4; GAD2; PRKCG
Dopaminergic synapse
PPP2R5B; GRIN2B; CREB3L1; CALY; MAOB; SCN1A; GNB4; CREB3L3; MAPK12; KCNJ6
Morphine addiction
ADRBK2; PRKCA; PRKCB; GABRA3; GNG3; GABRA4; PDE4C; PDE4D; GABRQ; ARRB2
Alcoholism
H2AFV; HIST1H2BC; KRAS; HIST1H4J; GM14479; HIST1H2AB; BDNF; GM14482; HIST3H2BB-PS; HDAC10
Pathways in cancer
F2R; PTK2; TFG; GNAI3; PDGFRA; VHL; AGTR1A; DAPK3; GNAI2; RASGRP3

Protein Function

GNG2 has several biochemical functions, for example, G-protein beta-subunit binding, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GNG2 itself. We selected most functions GNG2 had, and list some proteins which have the same functions with GNG2. You can find most of the proteins on our site.
Function
Related Protein
Function G-protein beta-subunit binding
Related Protein RGS11; GNG2; RASD2; F2RL1; OPRM1; CCT5; RGS9; RGS7; F2R; GNG13
Function signal transducer activity
Related Protein OLFR151; OLFR476; TAS2R107; FPR-RS6; OLFR491; GNAI2A; OLFCS2; OLFR488; BCAR1; OLFR507

Interacting Protein

GNG2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNG2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNG2.
GNAI1; Fnta