gng5
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  • Official Full Name
  • guanine nucleotide binding protein (G protein), gamma 5
  • Synonyms
  • GNG5;guanine nucleotide binding protein (G protein), gamma 5;guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5;FLJ92393;
Cat.#:GNG5-5071HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GNG5 Protein, GST-tagged
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Cat.#:GNG5-13365HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GNG5, GST-tagged
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Cat.#:GNG5-2607RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat GNG5 Protein
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Cat.#:GNG5-1906RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey GNG5 Protein, His-tagged
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Cat.#:GNG5-5618CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken GNG5
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Cat.#:GNG5-12747ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GNG5
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Cat.#:GNG5-5851HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GNG5 293 Cell Lysate
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Involved Pathway

GNG5 involved in several pathways and played different roles in them. We selected most pathways GNG5 participated on our site, such as Ras signaling pathway, Chemokine signaling pathway, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNG5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ras signaling pathway
PLA2G12A; LOC608458; GRIN2B; PIK3R2; FLT4; FGF5; FGF19; GRIN1; MAP2K1; GNG4
Chemokine signaling pathway
CX3CR1; CCL27; GM13306; IL-8; STAT5B; CRKL; NFKBIB; CCL24; BCAR1; CXCL14
PIK-Akt signaling pathway
MTCP1; RHEB; ITGA3; LPAR3; RPTOR; ITGB7; THBS3; CREB3L2; KLK1B4; KITLG
Circadian entrainment
GNG7; GRIN2B; CALM3; NOS1AP; Adcy4; KCNJ5; GNAI2; GNAO1; GUCY1A3; KCNJ9
Retrograde endocannabinoid signaling
GABRD; MAPK13; PRKACB; ITPR1; PLCB1; RIMS1; GNG12; GNG3; GNB3; GRIA3
Glutamatergic synapse
GRIA2; GRM6; PRKCB; SHANK3; GNG10; PLA2G4F; PLA2G4C; GRIA1; GNAQ; GNGT1
Cholinergic synapse
CHRM1; GNG13; CHRM4; PRKCG; PIK3CD; GNAQ; PRKCA; CAMK2D; PLCB4; CAMK2A
Serotonergic synapse
ARAF; TPH1; BRAF; KCNN2; HTR1A; CYP2C70; CYP2C39; SLC18A2; TPH2; PRKACB
GABAergic synapse
GNAO1; GNAI2; GNG2; GABRR3; GABRA4; HAP1; PRKACG; GAD1; GNG11; SLC38A2
Dopaminergic synapse
GNG5; GRIN2A; PPP3CC; DRD5; GNG10; MAPK13; CAMK2B; PPP2R1B; GNG4; GNG8
Morphine addiction
GNG8; PDE8B; PDE8A; GABBR2; GRK6; GABRB1; ADRBK2; GABRA3; GABRD; DRD1A
Alcoholism
GNG12; HIST1H4D; PPP1CC; GNGT1; H2AFX; GNB3; CALM4; ATF2; ATF4; HIST1H2AK
Pathways in cancer
ITGA3; RUNX1; CCDC6; LAMA2; HDAC1; ITGA2B; NRAS; SKP2; CXCR4; GNB3

Protein Function

GNG5 has several biochemical functions, for example, GTPase activity, PDZ domain binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GNG5 itself. We selected most functions GNG5 had, and list some proteins which have the same functions with GNG5. You can find most of the proteins on our site.
Function
Related Protein
Function GTPase activity
Related Protein RAB11BB; GPN1; RAB5B; RAB10; RHOT1A; RAB40C; RAB1BA; MFN2; MXG; IFT22
Function PDZ domain binding
Related Protein CRIPT; LIN7B; GIPC1; GNG5; CCDC88C; ARHGAP29; LRP2; NLGN1; ACCN3; DLC
Function protein binding
Related Protein KMT2E; STK38L; TBC1D5; MLST8; TNKS; PEA15; CCBE1; NANOS3; PENK; MEX3C
Function signal transducer activity
Related Protein TAAR8A; MAVS; ATP2C1; GNAZ; OR103-4; SH2B3; PRKCE; GPR113; TACR3L; OMPB

Interacting Protein

GNG5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNG5 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNG5.
GOLGA2; TRAF1; KRT31; KRT40; MDFI; EPS15L1; AMOTL2

GNG5 Related Articles

Padigel, UM; Stein, L; et al. Signaling through G alpha i2 protein is required for recruitment of neutrophils for antibody-mediated elimination of larval Strongyloides stercoralis in mice. JOURNAL OF LEUKOCYTE BIOLOGY 81:1120-1126(2007).
Fabbri, E; Selva, C; et al. Identification and properties of a Gs protein in catfish liver membranes. GENERAL AND COMPARATIVE ENDOCRINOLOGY 125:340-348(2002).