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GNL3

  • Official Full Name

    guanine nucleotide binding protein-like 3 (nucleolar)

  • Overview

    May be required to maintain the proliferative capacity of stem cells and may play an important role in tumorigenesis.
  • Synonyms

    GNL3; guanine nucleotide binding protein-like 3 (nucleolar); Ns; guanine nucleotide-binding protein-like 3; nucleostemin; nucleolar GTP-binding protein 3;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GNL3-13370H Recombinant Human GNL3, His-tagged E.coli His 201-549a.a.
Human GNL3-5846HCL Recombinant Human GNL3 293 Cell Lysate HEK293 N/A
Human GNL3-5847HCL Recombinant Human GNL3 293 Cell Lysate HEK293 N/A
Human GNL3-5397HF Recombinant Full Length Human GNL3 Protein, GST-tagged In Vitro Cell Free System GST 549 amino acids
Human GNL3-5081H Recombinant Human GNL3 Protein, GST-tagged Wheat Germ GST
Mouse GNL3-7046M Recombinant Mouse GNL3 Protein Mammalian Cell His
Mouse GNL3-3779M Recombinant Mouse GNL3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GNL3-3779M-B Recombinant Mouse GNL3 Protein Pre-coupled Magnetic Beads HEK293
Rat GNL3-2611R Recombinant Rat GNL3 Protein Mammalian Cell His
Rat GNL3-2266R Recombinant Rat GNL3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GNL3-2266R-B Recombinant Rat GNL3 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish GNL3-448Z Recombinant Zebrafish GNL3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GNL3 Related Articles

GNL3 involved in several pathways and played different roles in them. We selected most pathways GNL3 participated on our site, such as Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ribosome biogenesis in eukaryotesRNASEN;BMS1;RRP7A;RCL1;FCF1;EFTUD1;PWP2H;POP1;GTPBP4

GNL3 has several biochemical functions, for example, GTP binding, GTPase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GNL3 itself. We selected most functions GNL3 had, and list some proteins which have the same functions with GNL3. You can find most of the proteins on our site.

Function Related Protein
GTP bindingNUDT16;AGAP2;DIRAS1B;TRIM66;RHOBTB2;EHD1A;RAB30;GIMAP2;RHOUB
GTPase activityGNA15.1;IRGF1;DNM1A;RAB33A;MXA;ARF1;RAB15;RASD1;RAB3DA
poly(A) RNA bindingCPSF4;CHST13;PTBP2;UBE2O;FAM120B;HIST1H4M;PA2G4;IMMT;EIF4A3
protein bindingWDR6;CD46;PRAM1;COPS7B;NSUN4;RPL11;TMEM74;KCTD13;PIWIL1

GNL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GNL3.

AGO2; TERT; STAT3; PPP2R5A; ESR1; ESR2; PSTPIP1; SMNDC1; CIAO1; MYC; TP53

Tsai, RYL; et al. Turning a new page on nucleostemin and self-renewal. JOURNAL OF CELL SCIENCE 127:3885-3891(2014).
Nakajima, TE; Yoshida, H; et al. Nucleostemin and TWIST as predictive markers for recurrence after neoadjuvant chemotherapy for esophageal carcinoma. CANCER SCIENCE 103:233-238(2012).
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