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GNL3L

  • Official Full Name

    guanine nucleotide binding protein-like 3 (nucleolar)-like

  • Overview

    The protein encoded by this gene appears to be a nucleolar GTPase that is essential for ribosomal pre-rRNA processing and cell proliferation. Two transcript variants encoding the same protein have been found for this gene.
  • Synonyms

    GNL3L; guanine nucleotide binding protein-like 3 (nucleolar)-like; guanine nucleotide-binding protein-like 3-like protein; FLJ10613; novel GTPase; RP11-353K22.1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GNL3L-13371H Recombinant Human GNL3L, GST-tagged E.coli GST C-term-348a.a.
Human GNL3L-297HCL Recombinant Human GNL3L lysate HEK293 N/A
Human GNL3L-5398HF Recombinant Full Length Human GNL3L Protein, GST-tagged In Vitro Cell Free System GST 582 amino acids
Human GNL3L-5083H Recombinant Human GNL3L Protein, GST-tagged Wheat Germ GST
Human GNL3L-1121H Recombinant Human GNL3L Protein (1-582 aa), His-SUMO-tagged E.coli His/SUMO 1-582 aa
Mouse GNL3L-7047M Recombinant Mouse GNL3L Protein Mammalian Cell His
Mouse GNL3L-3780M-B Recombinant Mouse GNL3L Protein Pre-coupled Magnetic Beads HEK293
Mouse GNL3L-3780M Recombinant Mouse GNL3L Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish GNL3L-863Z Recombinant Zebrafish GNL3L Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GNL3L Related Articles

GNL3L involved in several pathways and played different roles in them. We selected most pathways GNL3L participated on our site, such as Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNL3L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ribosome biogenesis in eukaryotesUTP14C;POP4;RBM28;NOP58;PWP2H;NOB1;XRN1;UTP18;GTPBP4

GNL3L has several biochemical functions, for example, GTP binding, GTPase activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GNL3L itself. We selected most functions GNL3L had, and list some proteins which have the same functions with GNL3L. You can find most of the proteins on our site.

Function Related Protein
GTP bindingAK4;DNM1A;TUBE1;RAB1BB;RAB25A;GMPPAA;IRGF4;TPX2;GNL3L
GTPase activityRAB27B;EFTUD1;RRAGCB;RAB17;EEF1A2;DNM2B;MRAS;RHOG;IRGF1
poly(A) RNA bindingUBAP2L;UBFD1;SRSF1;PTRF;PCBP4;NGDN;SR140;NVL;LRP1
protein bindingLNPEP;RNF11;CCDC36;GEMIN7;EIF2AK3;IL15RA;TARDBP;PFKM;PVRL2

GNL3L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNL3L here. Most of them are supplied by our site. Hope this information will be useful for your research of GNL3L.

ALAS1; MDM2; LZTS2; ROPN1; TP53; LDOC1

Lin, T; Meng, LJ; et al. Nucleostemin and GNL3L exercise distinct functions in genome protection and ribosome synthesis, respectively. JOURNAL OF CELL SCIENCE 127:2302-2312(2014).
Essers, PB; Pereboom, TC; et al. A comparative study of nucleostemin family members in zebrafish reveals specific roles in ribosome biogenesis.. DEVELOPMENTAL BIOLOGY 385:304-315(2014).
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