GNPAT
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Official Full Name
glyceronephosphate O-acyltransferase
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Overview
This gene encodes an enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids. Mutations in this gene are associated with rhizomelic chondrodysplasia punctata. -
Synonyms
GNPAT; glyceronephosphate O-acyltransferase; dihydroxyacetone phosphate acyltransferase; DAP AT; DAPAT; DHAPAT; Acyl CoA dihydroxyacetonephosphateacyltransferase; DHAP AT; EC 2.3.1.42; Glyceronephosphate O acyltransferase; OTTHUMP00000036147; DHAP-AT; OTTHUMP00000036148; glycerone-phosphate O-acyltransferase; acyl-CoA:dihydroxyacetonephosphateacyltransferase; DAP-AT;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- GNPAT Related Articles
GNPAT involved in several pathways and played different roles in them. We selected most pathways GNPAT participated on our site, such as Glycerophospholipid metabolism, Peroxisome, which may be useful for your reference. Also, other proteins which involved in the same pathway with GNPAT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycerophospholipid metabolism | LPIN2;MBOAT7;AGPAT3;MBOAT2;TAE1;PHYKPL;PCYT2;PPAP2C;MBOAT1 |
| Peroxisome | MPV17;PHYH;HACL1;PMVK;DAO.2;DAO.3;ACSL1B;ECH1;ANI_1_2390104 |
GNPAT has several biochemical functions, for example, glycerone-phosphate O-acyltransferase activity, palmitoyl-CoA hydrolase activity, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GNPAT itself. We selected most functions GNPAT had, and list some proteins which have the same functions with GNPAT. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| glycerone-phosphate O-acyltransferase activity | |
| palmitoyl-CoA hydrolase activity | ACOT2;THEM5;GNPAT;ACOT7;ACOT5;THEM4;ACOT1;BAAT;ACOT8 |
| receptor binding | AMN;NRG3;FGF13B;TNFSF15;CD70;GNB2L1;TENM2;LAMA4;ITGA1 |
GNPAT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GNPAT here. Most of them are supplied by our site. Hope this information will be useful for your research of GNPAT.
HSPB1; GPR3; RAB35; PEX14; 1C; SLX4; PEX5
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