GPLD1
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Official Full Name
glycosylphosphatidylinositol specific phospholipase D1
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Overview
Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane. [provided by RefSeq, Jul 2008] -
Synonyms
GPLD1; glycosylphosphatidylinositol specific phospholipase D1; PLD; GPIPLD; PIGPLD; GPIPLDM; PIGPLD1; phosphatidylinositol-glycan-specific phospholipase D; GPI-PLD; PI-G PLD; GPI-specific phospholipase D; glycoprotein phospholipase D; glycosylphosphatidylinositol specific phospholipase D1, isoform 2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- Human Cell
- In Vitro Cell Free System
- Mammalian cells
- Wheat Germ
- C
- Myc
- DDK
- DYKDDDDK
- Flag
- GST
- His
- His (Fc)
- Avi
- MYC
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- GPLD1 Related Articles
- GPLD1 Related Research Area
GPLD1 involved in several pathways and played different roles in them. We selected most pathways GPLD1 participated on our site, such as Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPLD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Glycosylphosphatidylinositol(GPI)-anchor biosynthesis | PIGYL;PIGQ;PIGH;GPLD1;PIGC;PIGM;PIGW;PIGV;PIGO |
GPLD1 has several biochemical functions, for example, glycosylphosphatidylinositol phospholipase D activity, phospholipase D activity, sodium channel regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPLD1 itself. We selected most functions GPLD1 had, and list some proteins which have the same functions with GPLD1. You can find most of the proteins on our site.
Function | Related Protein |
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glycosylphosphatidylinositol phospholipase D activity | |
phospholipase D activity | GPLD1;PLD3;PLD2;PLD1A;HMOX1;PLD1;PLD4 |
sodium channel regulator activity | SCN3B;SCN2B;SGK2A;FXYD5;NEDD4L;PTPN3;GPD1L;FXYD6;SGK2 |
GPLD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPLD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPLD1.
- Q&As
- Reviews
Q&As (7)
Ask a questionGPLD1 works with other metabolic enzymes, coordinating carbohydrate and lipid metabolism.
Targeting GPLD1 offers potential in treating metabolic disorders by regulating liver metabolism.
GPLD1 is also involved in lipid metabolism, affecting fat processing and storage.
Altered GPLD1 activity is linked to various metabolic disorders, including diabetes and liver diseases.
GPLD1, a glycosylphosphatidylinositol-specific phospholipase, is involved in modulating liver metabolism and function.
Genetic variations in GPLD1 can lead to altered metabolic processing, impacting liver health and function.
It plays a role in glycogen metabolism, impacting glucose regulation in the liver.
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