ALDH18A1
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Official Full Name
aldehyde dehydrogenase 18 family, member A1
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
ALDH18A1 involved in several pathways and played different roles in them. We selected most pathways ALDH18A1 participated on our site, such as Arginine and proline metabolism, Metabolic pathways, Biosynthesis of amino acids, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALDH18A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Arginine and proline metabolism | DAO1;OAT;DAO.1;ALDH1B1;CARNS1;NOS3;ABP1;ARG1;ALDH3A2A |
| Metabolic pathways | SDHDA;UCK2B;DPYDB;CYP51;PYGL;CYP4A12A;DCT;CYP3A65;GMPPAA |
| Biosynthesis of amino acids | PC;CBSB;ALDOAA;ASL2;TKTL1;PFKM;BCAT2;PFKMA;MAT2B |
ALDH18A1 has several biochemical functions, for example, ATP binding, glutamate 5-kinase activity, glutamate-5-semialdehyde dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALDH18A1 itself. We selected most functions ALDH18A1 had, and list some proteins which have the same functions with ALDH18A1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | ATP5B;CCT4;GK5;GCLC;GM7168;ERN1;PIK3R4;PAPOLG;SMYHC1 |
| glutamate 5-kinase activity | |
| glutamate-5-semialdehyde dehydrogenase activity | |
| poly(A) RNA binding | HIST1H4N;CPNE3;FNDC3A;TRMT1L;LRPPRC;ERH;RPL7A;DNTTIP2;XPO5 |
| protein binding | EXOC3;DLC1;KIRREL2;KRT2;HSPB9;FAM71C;KIF2C;DDL-2;THOC2 |
ALDH18A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALDH18A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALDH18A1.
AGTRAP; CMTM5; Cbx1; Trim69; Haus1; Mical3; ZRANB1; 15-deoxy-delta(12,14; MYC; VCAM1; ICT1; LLGL2; Lats2; C1qbp
- Q&As
- Reviews
Q&As (7)
Ask a questionALDH18A1 encodes delta-1-pyrroline-5-carboxylate synthetase, an enzyme involved in proline biosynthesis.
Yes, ALDH18A1 is associated with amino acid metabolism, specifically in the synthesis of the amino acid proline.
ALDH18A1 contributes to cellular homeostasis by regulating the production of proline, an amino acid with various cellular functions.
Mutations in ALDH18A1 can lead to a rare genetic disorder called type I hyperprolinemia, characterized by elevated levels of proline in the blood.
ALDH18A1 participates in the conversion of glutamate to pyrroline-5-carboxylate, a crucial step in proline biosynthesis.
Therapeutic interventions targeting ALDH18A1 may be explored for conditions related to proline metabolism, but this would require careful consideration due to the essential role of proline in various cellular processes.
ALDH18A1 is typically located in the mitochondria, where it carries out the biosynthesis of proline.
Customer Reviews (3)
Write a reviewIts speed in modulating signaling pathways allowed us to obtain results quickly, saving valuable time.
The product's ability to accelerate research progress made it invaluable for time-critical projects.
Time-sensitive assays were notably improved by the swift effects of the product.
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