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GPSM1

  • Official Full Name

    G-protein signaling modulator 1

  • Overview

    G-protein signaling modulators (GPSM) play diverse functional roles through their interaction with G-protein subunits. This gene encodes a receptor-independent activator of G protein signaling, which is one of several factors that influence the basal activity of G protein signaling systems. The protein contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory (GPR) motifs in its C-terminal half. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    GPSM1; G-protein signaling modulator 1; G protein signalling modulator 1 (AGS3 like, C. elegans); G-protein-signaling modulator 1; AGS3; AGS3 homolog (C. elegans); DKFZP727I051; Activator of G-protein signaling 3; AGS3 homolog; C10a; G protein signaling modulator 1 (AGS3 like, C. elegans); GPSM1_HUMAN; 1810037C22Rik; G-protein signaling modulator 1 (AGS3-like, C. elegans); G-protein signalling modulator 1 (AGS3-like, C. elegans);

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GPSM1-750HCL Recombinant Human GPSM1 cell lysate N/A
Human GPSM1-2237H Recombinant Human GPSM1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human GPSM1-5298H Recombinant Human GPSM1 Protein, GST-tagged Wheat Germ GST
Human GPSM1-5562HF Recombinant Full Length Human GPSM1 Protein, GST-tagged In Vitro Cell Free System GST 434 amino acids
Human GPSM1-4519H Recombinant Human GPSM1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse GPSM1-7225M Recombinant Mouse GPSM1 Protein Mammalian Cell His
Mouse GPSM1-3899M-B Recombinant Mouse GPSM1 Protein Pre-coupled Magnetic Beads HEK293
Mouse GPSM1-3899M Recombinant Mouse GPSM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Gpsm1-3298M Recombinant Mouse Gpsm1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat GPSM1-2674R Recombinant Rat GPSM1 Protein Mammalian Cell His
Rat GPSM1-2328R-B Recombinant Rat GPSM1 Protein Pre-coupled Magnetic Beads HEK293
Rat GPSM1-2328R Recombinant Rat GPSM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GPSM1 Related Articles

GPSM1 involved in several pathways and played different roles in them. We selected most pathways GPSM1 participated on our site, such as Cocaine addiction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPSM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cocaine addictionGNAI2;ATF6B;DLG4;BDNF;CREB5;NFKB1;TH;PRKACG;PRKACA

GPSM1 has several biochemical functions, for example, GDP-dissociation inhibitor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GPSM1 itself. We selected most functions GPSM1 had, and list some proteins which have the same functions with GPSM1. You can find most of the proteins on our site.

Function Related Protein
GDP-dissociation inhibitor activityITGB1BP1;SH3BP4A;GPSM1;RANBP1;GDI1;GPSM1B;GPSM2L;SH3BP4;RGS14
protein bindingGAPDH;KHDC3;OGT;PSMG1;MTPAP;PPP1R11;HSBP1;PMF1;UBA6

GPSM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPSM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPSM1.

ZBED1; DAZAP2; TRIP13; CCDC158; USHBP1

Giguere, PM; Billard, MJ; et al. G-protein signaling modulator-3, a gene linked to autoimmune diseases, regulates monocyte function and its deficiency protects from inflammatory arthritis. MOLECULAR IMMUNOLOGY 54:193-198(2013).
Sugihara, M; Morita, H; et al. Dual Signaling Pathways of Arterial Constriction by Extracellular Uridine 5 '-Triphosphate in the Rat. JOURNAL OF PHARMACOLOGICAL SCIENCES 115:293-308(2011).
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