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GPSM2

Official Full Name

G-protein signaling modulator 2
Overview

The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82).
Synonyms

GPSM2; G-protein signaling modulator 2; deafness, autosomal recessive 82 , DFNB82, G protein signalling modulator 2 (AGS3 like, C. elegans); G-protein-signaling modulator 2; LGN; Pins; mosaic protein LGN; G-protein signalling modulator 2 (AGS3-like, C. e;

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GPSM2-13504H	Recombinant Human GPSM2, GST-tagged	E.coli	GST	N-term-353a.a.	$319 / 25ug
Human	GPSM2-5765HCL	Recombinant Human GPSM2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	GPSM2-5300H	Recombinant Human GPSM2 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GPSM2-2337H	Recombinant Human GPSM2 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	GPSM2-5564HF	Recombinant Full Length Human GPSM2 Protein, GST-tagged	In Vitro Cell Free System	GST	677 amino acids	Inquiry
Mouse	Gpsm2-3299M	Recombinant Mouse Gpsm2 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Zebrafish	GPSM2-10745Z	Recombinant Zebrafish GPSM2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
GPSM2 Related Articles

GPSM2 involved in several pathways and played different roles in them. We selected most pathways GPSM2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GPSM2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

GPSM2 has several biochemical functions, for example, GTPase regulator activity, identical protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GPSM2 itself. We selected most functions GPSM2 had, and list some proteins which have the same functions with GPSM2. You can find most of the proteins on our site.

Function	Related Protein
GTPase regulator activity	RGS12B;ARL2BP;RGS14A;GPSM2;RIMS1;TSC1;GPSM3;PCP2;RUNDC3A
identical protein binding	AKT1;SAFB2;PYCARD;SOD2;RILPL2;TGFB3;CLDNG;C;MRAP2
protein binding	TPM1;TOP3A;RBMX;FLI1;IL17A;TDRD7;PDP1;CA;CREB3L3

GPSM2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPSM2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPSM2.

NUMA1; GNAI1; GLIS2; pins; AASDH; PABPC4L

Falola, MI; Wiener, HW; et al. Genomic Copy Number Variants: Evidence for Association with Antibody Response to Anthrax Vaccine Adsorbed. PLOS ONE 8:-(2013).