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GRAP2

  • Official Full Name

    GRB2-related adaptor protein 2

  • Overview

    This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript variants utilizing alternative polyA sites exist.
  • Synonyms

    GRAP2; GRB2-related adaptor protein 2; GRB2-related adapter protein 2; GADS; GRBLG; GrbX; Grf40; Mona; grf-40; GRB-2-like protein; adapter protein GRID; grf40 adapter protein; SH3-SH2-SH3 adapter Mona; SH3-SH2-SH3 adaptor molecule; growth factor receptor-binding protein; GRB2-related protein with insert domain; hematopoietic cell-associated adapter protein GrpL; hematopoietic cell-associated adaptor protein GRPL; growth factor receptor-bound protein 2-related adaptor protein 2; P38; GRID; GRPL; GRB2L; GRAP-2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GRAP2-3432H Recombinant Human GRAP2 protein, His-tagged E.coli His
Human GRAP2-27308TH Recombinant Human GRAP2, His-tagged E.coli His 330 amino acids
Human GRAP2-13516H Recombinant Human GRAP2, GST-tagged E.coli GST 1-330a.a.
Human GRAP2-5757HCL Recombinant Human GRAP2 293 Cell Lysate HEK293 N/A
Human GRAP2-5318HF Recombinant Full Length Human GRAP2 Protein, GST-tagged In Vitro Cell Free System GST 330 amino acids
Human GRAP2-3176H Recombinant Human GRAP2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human GRAP2-3303H Recombinant Human GRAP2 Protein (Val77-Val325), N-His tagged E.coli N-His Val77-Val325
Human GRAP2-301176H Recombinant Human GRAP2 protein, GST-tagged E.coli GST Met1-Arg330
Human GRAP2-5033H Recombinant Human GRAP2 Protein, GST-tagged Wheat Germ GST
Mouse GRAP2-7243M Recombinant Mouse GRAP2 Protein Mammalian Cell His
Mouse Grap2-3302M Recombinant Mouse Grap2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Grap2-1602M Recombinant Mouse Grap2 protein, His & T7-tagged E.coli His/T7 Arg20~Ala262 (Accession # O89100)
Mouse GRAP2-3911M Recombinant Mouse GRAP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GRAP2-3911M-B Recombinant Mouse GRAP2 Protein Pre-coupled Magnetic Beads HEK293
Rat Grap2-1603R Recombinant Rat Grap2 protein, His & T7-tagged E.coli His/T7 Asp15~Glu247 (Accession # Q3KR57)
Rhesus Macaque GRAP2-1969R Recombinant Rhesus monkey GRAP2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque GRAP2-1790R Recombinant Rhesus Macaque GRAP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque GRAP2-1790R-B Recombinant Rhesus Macaque GRAP2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

GRAP2 involved in several pathways and played different roles in them. We selected most pathways GRAP2 participated on our site, such as T cell receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRAP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
T cell receptor signaling pathwayPRKCQ;CD8B1;CD4;PAK7;PIK3CD;BCL10;PPP3CA;CBL;KRAS

GRAP2 has several biochemical functions, for example, chloride channel activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GRAP2 itself. We selected most functions GRAP2 had, and list some proteins which have the same functions with GRAP2. You can find most of the proteins on our site.

Function Related Protein
chloride channel activityCLCA3;SLC26A2;SLC26A5;SLC26A11;CLCN4;GABRA5;CLIC5;GABRD;GABRA1
protein bindingDUSP14;FAM32A;TFDP2;GBF1;TES;CENPA;SPAG9;SNAP47;FAM59A

GRAP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRAP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GRAP2.

LCP2; PTPN23

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