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GRIP1

  • Official Full Name

    glutamate receptor interacting protein 1

  • Overview

    This gene encodes a member of the glutamate receptor interacting protein family. The encoded scaffold protein binds to and mediates the trafficking and membrane organization of a number of transmembrane proteins. Alternatively spliced transcript variants encoding different isoforms have been described.
  • Synonyms

    GRIP1; glutamate receptor interacting protein 1; glutamate receptor-interacting protein 1; GRIP-1; AMPA receptor-interacting protein GRIP1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GRIP1-1747H Recombinant Human GRIP1 protein, His & T7-tagged E.coli His/T7 Arg79~Thr268 (Accession # Q9Y3R0)
Human GRIP1-12H Recombinant Human GRIP1 Protein, GST-tagged Wheat Germ GST 851 a.a. - 950 a.a.
Human GRIP1-5741HCL Recombinant Human GRIP1 293 Cell Lysate HEK293 N/A
Human GRIP1-113H Recombinant Human GRIP1 protein, His-tagged E. coli His 702-964 aa
Human GRIP1-2863H Recombinant Human GRIP1 Protein (Gly874-Glu1073), N-His tagged E.coli N-His Gly874-Glu1073
Mouse GRIP1-7277M Recombinant Mouse GRIP1 Protein Mammalian Cell His
Mouse GRIP1-3935M-B Recombinant Mouse GRIP1 Protein Pre-coupled Magnetic Beads HEK293
Mouse GRIP1-3935M Recombinant Mouse GRIP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GRIP1-2707R Recombinant Rat GRIP1 Protein Mammalian Cell His
Rat GRIP1-2361R Recombinant Rat GRIP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GRIP1-2361R-B Recombinant Rat GRIP1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish GRIP1-3973Z Recombinant Zebrafish GRIP1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GRIP1 Related Articles

GRIP1 involved in several pathways and played different roles in them. We selected most pathways GRIP1 participated on our site, such as BDNF signaling pathway, Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity, Neuronal System, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRIP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
BDNF signaling pathwayCDK5;CDKL5;LINGO1;FRS2;MAP3K2;CNR1;BCL2L11;EIF4EBP1;KCNN2
Glutamate Binding, Activation of AMPA Receptors and Synaptic PlasticityCACNG2;HAND2;NSFA;CACNG3;PICK1;GRIP1;MYO6;AKAP5;NSFB
Neuronal SystemCHRNA1;CACFD1;ABCC9;KCND1;KCNH6;KCNK7;PPFIA2;KCNAB1;KCNH6A
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic CellGRIP1;AKAP5;CAMKK1B;CHRNA5;CHRND;NSFA;PICK1;CHRNE;MYO6
Trafficking of AMPA receptorsHAND2;PICK1;GRIP1
Trafficking of GluR2-containing AMPA receptorsHAND2;PICK1;GRIP1
Transmission across Chemical SynapsesPICK1;PPFIA2;NCALDA;SLC6A11;SLC1A2B;SLC1A3A;SLC18A3A;Apba1;GABRR2A

GRIP1 has several biochemical functions, for example, androgen receptor binding, beta-catenin binding, glucocorticoid receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GRIP1 itself. We selected most functions GRIP1 had, and list some proteins which have the same functions with GRIP1. You can find most of the proteins on our site.

Function Related Protein
androgen receptor bindingCCNE1;RNF6;FHL2;DDX5;WIPI1;RNF4;KDM3A;PRPF6;PIAS1
beta-catenin bindingAPC;DACT2;MED12L;APC2;Ar;SMAD7;PROP1;BCL9;CDH5
glucocorticoid receptor bindingEP300;GRIP1;YWHAH;ETS2;NRIP1;CEBPB;STAT5B;NR4A2;FKBP4
protein C-terminus bindingATF4;SIAH1;LCK;TRIM3;DLG1;SP1;PHB;PHB2;MID1IP1
protein bindingTMEM185A;SGCG;TMX3;LEPROT;ZNF274;CDKN2A;IKZF3;FGFR2;FAM168A
receptor signaling complex scaffold activityNCK1;CARD10;RGS14;ROPN1B;MAPK8IP3;G3BP2;GRIP1;GRIP2A;CD3G
transcription coactivator activityGMEB1;CTNNB1;GTF2A1;ARID1A;JUPA;NR2F1;SMARCA4;SCAND1;ARNT

GRIP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRIP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GRIP1.

ESR1; PSMB9; IRF3; KANK2; NR3C1; PRLHR; NCOA1; ZYX; PRKD2; YWHAB; Lats2; NCOA3

Dobroyolna, J; Chinenov, Y; et al. Glucocorticoid-Dependent Phosphorylation of the Transcriptional Coregulator GRIP1. MOLECULAR AND CELLULAR BIOLOGY 32:730-739(2012).
Selak, S; Paternain, AV; et al. A Role for SNAP25 in Internalization of Kainate Receptors and Synaptic Plasticity. NEURON 63:357-371(2009).
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