grip1
Share
  • Official Full Name
  • glutamate receptor interacting protein 1
  • Background
  • This gene encodes a member of the glutamate receptor interacting protein family. The encoded scaffold protein binds to and mediates the trafficking and membrane organization of a number of transmembrane proteins. Alternatively spliced transcript variants encoding different isoforms have been described.
  • Synonyms
  • GRIP1; glutamate receptor interacting protein 1; glutamate receptor-interacting protein 1; GRIP-1; AMPA receptor-interacting protein GRIP1
Cat.#:GRIP1-12HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GRIP1 Protein, GST-tagged
+Inquiry
Cat.#:GRIP1-1747HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GRIP1 protein, His & T7-tagged
+Inquiry
Cat.#:GRIP1-7277MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GRIP1 Protein
+Inquiry
Cat.#:GRIP1-2707RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat GRIP1 Protein
+Inquiry
Cat.#:GRIP1-3973ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GRIP1
+Inquiry
Cat.#:GRIP1-5741HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GRIP1 293 Cell Lysate
+Inquiry

Involved Pathway

GRIP1 involved in several pathways and played different roles in them. We selected most pathways GRIP1 participated on our site, such as BDNF signaling pathway, Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity, Neuronal System, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRIP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
BDNF signaling pathway
KCNN2; LINGO1; CNR1; SYN1; CDK5; YBX1; EIF4EBP1; CDH2; EGR1; GNB2L1
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity
NSFA; GRIP1; MYO6; AKAP5; PICK1; HAND2; CACNG2; CACNG3; NSFB
Neuronal System
SLC1A7A; KCNK16; KCNJ1A.2; KCNN1B; MYO6; KCNH8; LIN7B; KCNAB2B; GNGT2B; KCNJ1A.3
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
DLG1L; NSFB; CHRNE; PICK1; CAMKK1B; CHRNA5; HAND2; CHRND; AKAP5; CHRNA2
Trafficking of AMPA receptors
GRIP1; PICK1; HAND2
Trafficking of GluR2-containing AMPA receptors
PICK1; GRIP1; HAND2
Transmission across Chemical Synapses
SYT1A; SLC1A7B; NCALDA; SLC17A7A; SLC1A2B; SLC1A3B; ARL6IP5; SLC6A11; ARL6IP5A; SYN2

Protein Function

GRIP1 has several biochemical functions, for example, androgen receptor binding, beta-catenin binding, glucocorticoid receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GRIP1 itself. We selected most functions GRIP1 had, and list some proteins which have the same functions with GRIP1. You can find most of the proteins on our site.
Function
Related Protein
Function androgen receptor binding
Related Protein KDM1A; TGFB1I1; TRIM68; FOXH1; PIAS2; BRCA1; NCOA1; PRMT2; CALR; NCOA3
Function beta-catenin binding
Related Protein SOX9; GRIP1; DACT3; CTNNA3; BTRC; PTPRK; GSK3B; DACT1; TBL1X; PTPRJ
Function glucocorticoid receptor binding
Related Protein STAT5B; YWHAH; ETS2; EP300; GRIP1; NR4A2; FKBP4; CEBPB; NRIP1; STAT3
Function protein C-terminus binding
Related Protein HRAS; JAK2; XRCC5; PHB2; TAX1BP3; SHANK3; VGLL3; MSH2; ABL1; MYO1C
Function protein binding
Related Protein FZD2; C17orf82; TIMM44; KRT40; ADI1; CCBL1; RNF14; GATSL3; TNFRSF10A; UBE2G2
Function receptor signaling complex scaffold activity
Related Protein GRIP2A; DEDD2; RGS14; NUP62; MAPK8IP3; SPAG9; CD3E; SHANK1; LDLRAP1; ROPN1B
Function transcription coactivator activity
Related Protein SERTAD2; AIP; TFDP1A; TFAP2B; TAF1; MED17; NR1H3; YAF2; BIRC2; RUNX1

Interacting Protein

GRIP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRIP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GRIP1.
ESR1; PSMB9; IRF3; KANK2; NR3C1; PRLHR; NCOA1; ZYX; PRKD2; YWHAB; Lats2; NCOA3

GRIP1 Related Articles

Dobroyolna, J; Chinenov, Y; et al. Glucocorticoid-Dependent Phosphorylation of the Transcriptional Coregulator GRIP1. MOLECULAR AND CELLULAR BIOLOGY 32:730-739(2012).
Selak, S; Paternain, AV; et al. A Role for SNAP25 in Internalization of Kainate Receptors and Synaptic Plasticity. NEURON 63:357-371(2009).