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GSTT2

  • Official Full Name

    glutathione S-transferase, theta 2

  • Overview

    Glutathione S-transferase (GSTs) theta 2 (GSTT2) is a member of a superfamily of proteins that catalyze the conjugation;of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five;main classes: Alpha, Mu, Pi, Theta, and Zeta. The theta class members GSTT1 and GSTT2 share 55% amino acid sequence;identity and both are thought to have an important role in human carcinogenesis. The theta genes have a similar;structure, being composed of five exons with identical exon/intron boundaries.
  • Synonyms

    GSTT2; glutathione S-transferase, theta 2; glutathione S-transferase theta-2; EC 2.5.1.18; Glutathione S transferase 12; Glutathione S transferase Yrs Yrs; Glutathione S-transferase theta-2B; GST 12 12; GST class theta 2; GST class-theta-2; GST T2; GSTT 2; GSTT2 protein; GSTT2_HUMAN; GSTT2B; MGC182032; OTTHUMP00000198491; OTTHUMP00000198492; Yrs; mGSTT2; AI266894;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GSTT2-13583H Recombinant Human GSTT2, GST-tagged E.coli GST 1-244a.a.
Human GSTT2-4430H Recombinant Human GSTT2 Protein, GST-tagged Wheat Germ GST
Human GSTT2-2665H Recombinant Human GSTT2 protein, His & T7-tagged E.coli His/T7 Arg15~Ala235 (Accession # P0CG29)
Human GSTT2-5708HCL Recombinant Human GSTT2 293 Cell Lysate HEK293 N/A
Human GSTT2-3369HF Recombinant Full Length Human GSTT2 Protein, GST-tagged In Vitro Cell Free System GST 244 amino acids
Human GSTT2-2559H Recombinant Human GSTT2 Protein (Arg15-Ala235), N-His tagged E.coli N-His Arg15-Ala235
Human GSTT2-5353H Recombinant Human GSTT2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse GSTT2-7342M Recombinant Mouse GSTT2 Protein Mammalian Cell His
Mouse Gstt2-2666M Recombinant Mouse Gstt2 protein, His & T7-tagged E.coli His/T7 Arg15~Ile216 (Accession # Q61133)
Mouse GSTT2-3982M-B Recombinant Mouse GSTT2 Protein Pre-coupled Magnetic Beads HEK293
Mouse GSTT2-3982M Recombinant Mouse GSTT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Gstt2-2667R Recombinant Rat Gstt2 protein, His & T7-tagged E.coli His/T7 Ala16~Arg242 (Accession # P30713)
Cynomolgus Monkey GSTT2-581C Recombinant Cynomolgus GSTT2 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey GSTT2-327C Recombinant Cynomolgus Monkey GSTT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey GSTT2-327C-B Recombinant Cynomolgus Monkey GSTT2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque GSTT2-1998R Recombinant Rhesus monkey GSTT2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque GSTT2-1819R Recombinant Rhesus Macaque GSTT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque GSTT2-1819R-B Recombinant Rhesus Macaque GSTT2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GSTT2 Related Articles

GSTT2 involved in several pathways and played different roles in them. We selected most pathways GSTT2 participated on our site, such as Glutathione metabolism, Metabolism of xenobiotics by cytochrome P, Drug metabolism - cytochrome P, which may be useful for your reference. Also, other proteins which involved in the same pathway with GSTT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glutathione metabolismGCLM;GGT7;GSTA3;GSTM4;PGD;ANPEPB;GSTK1;TXNDC12;GGCTB
Metabolism of xenobiotics by cytochrome PADH1;AKR7A2;CBR1L;GSTA1;GSTM1;EPHX1;DHDHL;GSTT1B;GSTT2B
Drug metabolism - cytochrome PUGT2B7;UGT2B15;ALDH3B1;GSTT1B;GSTA4;GSTA3;GSTP2;GSTO1;AOX3
Chemical carcinogenesisCYP3A41B;UGT1A4;GSTA1;CYP3A7;CYP2B19;GSTA4;GSTM2;ALDH3A1;CYP2C55

GSTT2 has several biochemical functions, for example, glutathione transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GSTT2 itself. We selected most functions GSTT2 had, and list some proteins which have the same functions with GSTT2. You can find most of the proteins on our site.

Function Related Protein
glutathione transferase activityGSTO1;GSTK1;LTC4S;GSTT1;GSTA;GSTAL;GSTM5;GSTT1B;HPGDS

GSTT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSTT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GSTT2.

Kano, S; Lo, B; et al. Altered Astrocyte-Microglia Communication as Potential Immune/Inflammatory Changes in Major Mental Illness. NEUROPSYCHOPHARMACOLOGY 39:S305-S306(2014).
Sueblinvong, V; Tseng, V; et al. TGF beta 1 Mediates Alcohol-Induced Nrf2 Suppression in Lung Fibroblasts. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 38:2731-2742(2014).
  • Q&As
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