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GUCY2C

  • Official Full Name

    guanylate cyclase 2C (heat stable enterotoxin receptor)

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Canine
  • Cynomolgus
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Insect Cell
  • Mammalian Cell
  • Wheat Germ
  • Yeast
  • C
  • His
  • Fc
  • Avi
  • GST
  • His (Fc)
  • Myc
  • His|Myc
  • human IgG1 Fc
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GUCY2C-1502H Active Recombinant Human GUCY2C protein, His-tagged, FITC-Labeled HEK293 His Ser24-Gln430
Human GUCY2C-1498H Active Recombinant Human GUCY2C protein, Fc-tagged, FITC-Labeled HEK293 Fc Ser24-Gln430
Human GUCY2C-1499H Active Recombinant Human GUCY2C protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Ser24-Gln430
Human GUCY2C-1501H Active Recombinant Human GUCY2C protein, Fc-Avi-tagged, Biotinylated HEK293 Fc-Avi Ser24-Gln430
Human GUCY2C-1503H Active Recombinant Human GUCY2C protein, Fc-tagged HEK293 Fc Ser24-Gln430
Human GUCY2C-13620H Recombinant Human GUCY2C, His-tagged E.coli His 25-372a.a.
Human GUCY2C-4492H Recombinant Human GUCY2C Protein, GST-tagged Wheat Germ GST
Human GUCY2C-5675HCL Recombinant Human GUCY2C 293 Cell Lysate HEK293 N/A
Human GUCY2C-669H Recombinant Human GUCY2C protein, Fc-tagged HEK293 human IgG1 Fc Ser24-Gln430
Human GUCY2C-4676H Active Recombinant Human GUCY2C Protein, His-tagged, PE-Labeled HEK293 His Ser 24 - Gln 430
Human GUCY2C-2766H Recombinant Human GUCY2C Protein (24-430 aa), His-tagged Insect Cell His 24-430 aa
Human GUCY2C-670H Recombinant Human GUCY2C protein(Met1-Gln430), His-tagged HEK293 C-His Met1-Gln430
Human GUCY2C-092H Recombinant Human GUCY2C protein, His-Avi-tagged HEK293 His-Avi Ser24-Gln430
Mouse GUCY2C-4010M Recombinant Mouse GUCY2C Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GUCY2C-1841M Recombinant Mouse GUCY2C protein, Fc-tagged HEK293 Fc Val 20 - Met 433
Mouse Gucy2c-5102M Recombinant Mouse Gucy2c protein, His&Myc-tagged HEK293 His&Myc 20-433aa
Mouse GUCY2C-2764M Recombinant Mouse GUCY2C Protein (20-433 aa), His-Myc-tagged Insect Cell His/Myc 20-433 aa
Mouse GUCY2C-1497M Recombinant Mouse GUCY2C protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Val20-Met433
Mouse GUCY2C-1842M Recombinant Mouse GUCY2C protein, His-tagged HEK293 His Val 20 - Met 433
Mouse GUCY2C-4010M-B Recombinant Mouse GUCY2C Protein Pre-coupled Magnetic Beads HEK293
Rat GUCY2C-2756R Recombinant Rat GUCY2C Protein Mammalian Cell His
Rat GUCY2C-2410R Recombinant Rat GUCY2C Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GUCY2C-2763R Recombinant Rat GUCY2C Protein (23-429 aa), His-Myc-tagged Insect Cell His/Myc 23-429 aa
Rat GUCY2C-2640R Recombinant Rat GUCY2C Protein (23-429 aa), His-Myc-tagged E.coli His/Myc 23-429 aa
Rat GUCY2C-2582R Recombinant Rat GUCY2C Protein (23-429 aa), His-Myc-tagged Yeast His/Myc 23-429 aa
Rat Gucy2c-5022R Recombinant Rat Gucy2c protein, His&Myc-tagged HEK293 His&Myc 23-429aa
Rat GUCY2C-2410R-B Recombinant Rat GUCY2C Protein Pre-coupled Magnetic Beads HEK293
Canine GUCY2C-1147C Recombinant Canine GUCY2C protein(Met1-Gln430), His-tagged HEK293 C-His Met1-Gln430
Cynomolgus GUCY2C-1500C Active Recombinant Cynomolgus GUCY2C protein, Fc-tagged HEK293 Fc Ser24-Gln430
Cynomolgus GUCY2C-449C Recombinant Cynomolgus GUCY2C protein, His-tagged HEK293 His Met1-Gln430
  • Involved Pathway
  • Protein Function
  • Interacting Protein

GUCY2C involved in several pathways and played different roles in them. We selected most pathways GUCY2C participated on our site, such as Purine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with GUCY2C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Purine metabolismAK4;RRM1;POLR2GL;ADCY1A;XDH;POLR2J3;NT5C;PDE6D;RRM2

GUCY2C has several biochemical functions, for example, ATP binding, GTP binding, NOT adenylate cyclase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GUCY2C itself. We selected most functions GUCY2C had, and list some proteins which have the same functions with GUCY2C. You can find most of the proteins on our site.

Function Related Protein
ATP bindingTBCK;CDKL3;UCK2B;PDXK;DGKE;IKBKE;HELQ;TOR1B;GLULB
GTP bindingTUBB5;GPN2;RAB5B;DNM3A;DNM1L;AGAP1;ARL17B;IRGF1;RAB2B
NOT adenylate cyclase activityNPR3;GUCY2C;GC2;GUCY1B3;NPR1;NPR2;NPR1A;GUCY2F;GC3
guanylate cyclase activityGUCY2E;GUCY2F;GUCY1B3;NPR1A;NPR2;NPR1;GUCY1A3;GUCY2C;GC2
protein bindingTSPAN2;ARNTL1B;UQCC1;FAM117B;TRDN;SDCCAG8;ALDH18A1;TXLNG;UBXN6
protein kinase activityIRAK1;CLK2B;STK30;Aatk;PRKD2;GRK1B;SIK2A;PAN3;PAK2B
toxic substance bindingNEFH;EPHX2;A4GALT;AZU1;GUCY2C;ASS1;H2-AB1;PHAX;DSG1

GUCY2C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GUCY2C here. Most of them are supplied by our site. Hope this information will be useful for your research of GUCY2C.

PDZD3; PDZK1; alsS

  • Q&As
  • Reviews

Q&As (7)

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How does GUCY2C contribute to the regulation of ion balance in intestinal cells? 11/17/2022

It regulates ion and water balance in intestinal cells, influencing fluid secretion.

Are there therapeutic strategies targeting GUCY2C for disease treatment? 09/05/2022

Therapeutic strategies include GUCY2C agonists for constipation and its use as a target in colorectal cancer immunotherapy.

How is GUCY2C implicated in colorectal cancer? 04/24/2022

GUCY2C acts as a tumor suppressor; its loss or mutation is linked to colorectal cancer.

What are the molecular mechanisms regulating GUCY2C expression and activity? 03/14/2022

GUCY2C expression and activity are regulated by various signaling pathways and post-translational modifications.

What is the main function of GUCY2C in cellular processes? 04/21/2021

GUCY2C produces cyclic GMP in response to ligand binding, modulating cellular functions.

What role does GUCY2C play in maintaining intestinal barrier function? 10/29/2020

It maintains the intestinal barrier, protecting against pathogens and inflammation.

In which tissues or cell types is GUCY2C predominantly expressed? 03/11/2019

GUCY2C is predominantly expressed in the intestinal epithelium.

Customer Reviews (3)

Write a review
Reviews
07/13/2022

    No complaints, worked well.

    04/03/2021

      Perfect for protein assays.

      10/30/2020

        Consistent quality, great results.

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