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Gabra4

  • Official Full Name

    gamma-aminobutyric acid (GABA) A receptor, alpha 4

  • Synonyms

    GABRA4; gamma-aminobutyric acid (GABA) A receptor, alpha 4; gamma-aminobutyric acid receptor subunit alpha-4; GABA(A) receptor; alpha 4; GABA(A) receptor, alpha 4;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Rat
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GABRA4-211H Recombinant Human GABRA4 Mammalian Cell His
Human GABRA4-6064HCL Recombinant Human GABRA4 293 Cell Lysate HEK293 N/A
Human GABRA4-4639H Recombinant Human GABRA4 Protein, GST-tagged Wheat Germ GST
Human GABRA4-1544H Recombinant Human GABRA4 Protein, His&GST-tagged E.coli N-His&GST Gln36-Tyr258
Human GABRA4-511H Recombinant Human GABRA4 Protein (36-258 aa), His-SUMO-tagged E.coli His/SUMO 36-258 aa
Human GABRA4-2995H Recombinant Human GABRA4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human GABRA4-5189HF Recombinant Full Length Human GABRA4 Protein, GST-tagged In Vitro Cell Free System GST 554 amino acids
Human GABRA4-2995H-B Recombinant Human GABRA4 Protein Pre-coupled Magnetic Beads HEK293
Rat GABRA4-2445R Recombinant Rat GABRA4 Protein Mammalian Cell His
Rat GABRA4-2101R Recombinant Rat GABRA4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GABRA4-2101R-B Recombinant Rat GABRA4 Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL14760HF Recombinant Full Length Human Gamma-Aminobutyric Acid Receptor Subunit Alpha-4(Gabra4) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (36-554)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Gabra4 Related Articles
  • Gabra4 Related Research Area

Gabra4 involved in several pathways and played different roles in them. We selected most pathways Gabra4 participated on our site, such as Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with Gabra4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuroactive ligand-receptor interactionTAAR14L;GRIN1B;GABRB1;HTR6;GRIA3B;AVPR1A;OPRD1A;GABRP;ADORA1
Retrograde endocannabinoid signalingGABRP;GABRG3;GNG12;DAGLB;Adcy4;GNAO1;ITPR3;SLC17A8;MAPK1
GABAergic synapseGABARAPL1;GPHN;GABRQ;GABRA3;SLC6A13;GNGT2;GABARAPL2;PLCL1;GABRR1
Nicotine addictionGABRG3;CHRNA6;GRIN2C;SLC17A7;GRIN2B;GABRA6;GRIN1;GABRB1;GRIA3

Gabra4 has several biochemical functions, for example, contributes_to GABA-A receptor activity, benzodiazepine receptor activity, chloride channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Gabra4 itself. We selected most functions Gabra4 had, and list some proteins which have the same functions with Gabra4. You can find most of the proteins on our site.

Function Related Protein
contributes_to GABA-A receptor activityGABRA4;GABRP;GABRA2;GABRG2;GABRG1;GABRQ;GABRA6A;GABRA3;GABRA6
benzodiazepine receptor activityGABRA2;GABRA6;GABRA3;GABRG2;GABRA4;TSPO
chloride channel activityGABRG2;SLC26A6;CLCA1;GABRA6A;GABRG1;CLIC2;CLCA3;CLIC5A;TTYH2L
inhibitory extracellular ligand-gated ion channel activityGABRA3;GABRA2;GABRE;GABRA6;GABRG3;GABRA6A;GABRA1;GABRG2;GABRG1

Gabra4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Gabra4 here. Most of them are supplied by our site. Hope this information will be useful for your research of Gabra4.

DGAT1

Srivastava, S; Cohen, J; et al. A Novel Variant in GABRB2 Associated with Intellectual Disability and Epilepsy. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164A:2914-2921(2014).
Quadrato, G; Elnaggar, MY; et al. Modulation of GABAA Receptor Signaling Increases Neurogenesis and Suppresses Anxiety through NFATc4. JOURNAL OF NEUROSCIENCE 34:8630-8645(2014).
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