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Gabra5

  • Official Full Name

    gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5

  • Synonyms

    GABRA5; gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5; gamma-aminobutyric acid receptor subunit alpha-5; GABAA receptor alpha5 subunit; GABA(A) receptor subunit alpha-5; ligand-gated ion channel subunit; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 5; A230018I05Rik;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GABRA5-13095H Recombinant Human GABRA5, GST-tagged E.coli GST 356-423a.a.
Human GABRA5-6063HCL Recombinant Human GABRA5 293 Cell Lysate HEK293 N/A
Human GABRA5-1352H Recombinant Human GABRA5 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human GABRA5-4641H Recombinant Human GABRA5 Protein, GST-tagged Wheat Germ GST
Human GABRA5-1545H Recombinant Human GABRA5 Protein, His-tagged E.coli N-His Gln32-Tyr259
Human GABRA5-5192HF Recombinant Full Length Human GABRA5 Protein, GST-tagged In Vitro Cell Free System GST 462 amino acids
Mouse Gabra5-487M Recombinant Mouse Gabra5 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat GABRA5-2446R Recombinant Rat GABRA5 Protein Mammalian Cell His
Rat GABRA5-2102R Recombinant Rat GABRA5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GABRA5-2102R-B Recombinant Rat GABRA5 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Gabra5 Related Articles
  • Gabra5 Related Research Area

Gabra5 involved in several pathways and played different roles in them. We selected most pathways Gabra5 participated on our site, such as Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with Gabra5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuroactive ligand-receptor interactionPTGIR;EDNRAA;GRIA4;DRD1A;IL12;GRID2;MC4R;CSH;P2RX4B
Retrograde endocannabinoid signalingAdcy4;ITPR1;MAPK12;GNG10;GNB4;FAAH;PRKACG;GABRE;GABRA4
GABAergic synapseGABRG1;SLC6A1;GNGT2;PRKACA;GABRA2;PRKACB;GABARAPL1;GNG11;GABRR1
Nicotine addictionGRIN2C;GABRR3;GABRA2;SLC17A6;GRIA1;GRIN1;SLC17A7;GRIA2;GABRR2

Gabra5 has several biochemical functions, for example, GABA receptor binding, contributes_to GABA-A receptor activity, contributes_to benzodiazepine receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Gabra5 itself. We selected most functions Gabra5 had, and list some proteins which have the same functions with Gabra5. You can find most of the proteins on our site.

Function Related Protein
GABA receptor bindingMAF1;PLCL1;GABARAPL2;GABARAPA;GABRA5;PLCL2;PPP2CA;JAKMIP1;GABRB1
contributes_to GABA-A receptor activityGABRR2A;GABRQ;GABRA6A;GABRA5;GABRP;GABRA2;GABRG1;GABRA6;GABRR3A
contributes_to benzodiazepine receptor activityGABRA6A;GABRA5;GABRE;GABRG1;GABRG3;GABRA1
chloride channel activityCLIC1;CLIC5;SLC26A6L;GABRA5;CLCA1;GABRA1;CLIC5B;GABRG3;CLCN7
inhibitory extracellular ligand-gated ion channel activityGABRA2;GABRA3;GABRA6;GABRA5;GABRB2;GABRG1;GABRA1;GABRA6A;GABRG3
receptor activityVMN1R40;NOTCH4;NRXN1;GFRA4A;ANTXR2;ANTXRL;NRXN3;CLEC4M;CADM2
transporter activityATP6V0B;SLC5A12;AP1G1;SLC13A5A;ABCC6;ABCB11;SLC23A2;TCIRG1;SLC25A38B

Gabra5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Gabra5 here. Most of them are supplied by our site. Hope this information will be useful for your research of Gabra5.

Ochoa-Lubinoff, CA; Berry-Kravis, EA; et al. Safety and Tolerability of RG1662, a Selective Negative Allosteric Modulator of the GABAA+/-5 Receptor (GABRA5), in Young Adults With Down Syndrome. JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS 36:S18-S18(2015).
Khan, WA; Rogan, PK; et al. Localized, non-random differences in chromatin accessibility between homologous metaphase chromosomes. MOLECULAR CYTOGENETICS 7:-(2014).
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