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Gabra6

Official Full Name

gamma-aminobutyric acid (GABA) A receptor, alpha 6
Overview

GABAA receptor subunit; part of a cerebellar receptor subtype, selective for antagonist of alcohol-induced motor incoordination and ataxia
Synonyms

GABRA6; gamma-aminobutyric acid (GABA) A receptor, alpha 6; gamma-aminobutyric acid receptor subunit alpha-6; GABA A; GABA A Receptor alpha 6polypeptide; GABA A receptor alpha 6; GABA A receptor subunit alpha 6; GABA subunit A receptor alpha 6; GABA(A) receptor subunit alpha-6; GABRA 6; Gamma aminobutyric acid A receptor alpha 6; Gamma aminobutyric acid GABA A receptor alpha 6; Gamma aminobutyric acid receptor subunit alpha 6; GBRA6_HUMAN; MGC116903; MGC116904; GABA-A receptor alpha-6 subunit; gamma-aminobutyric acid A receptor, alpha 6; gamma-aminobutyric acidA receptor, alpha 6; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 6;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GABRA6-13096H	Recombinant Human GABRA6, His-tagged	E.coli	His	329-424a.a.	$319 / 25ug
Human	GABRA6-4643H	Recombinant Human GABRA6 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GABRA6-1546H	Recombinant Human GABRA6 Protein, His-tagged	E.coli	N-His	Glu41-Gln207	Inquiry
Human	GABRA6-5194HF	Recombinant Full Length Human GABRA6 Protein, GST-tagged	In Vitro Cell Free System	GST	453 amino acids	Inquiry
Mouse	GABRA6-6148M	Recombinant Mouse GABRA6 Protein	Mammalian Cell	His		Inquiry
Mouse	GABRA6-3429M-B	Recombinant Mouse GABRA6 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	GABRA6-3429M	Recombinant Mouse GABRA6 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Gabra6-1547M	Recombinant Mouse Gabra6 Protein, His-tagged	E.coli	N-His	Gln20-Tyr242	Inquiry
Rat	GABRA6-2447R	Recombinant Rat GABRA6 Protein	Mammalian Cell	His		Inquiry
Rat	GABRA6-2103R-B	Recombinant Rat GABRA6 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	GABRA6-2103R	Recombinant Rat GABRA6 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Chicken	GABRA6-6615C	Recombinant Chicken GABRA6	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Gabra6 Related Articles
Gabra6 Related Research Area

Gabra6 involved in several pathways and played different roles in them. We selected most pathways Gabra6 participated on our site, such as Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with Gabra6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Neuroactive ligand-receptor interaction	CSH1;TAAR13D;CHRND;TAAR7A;GRIK3;THRA;MAS1;HTR1AA;TACR3L
Retrograde endocannabinoid signaling	GABRB3;MAPK3;SLC17A7;MAPK9;PTGS2;GNG10;MAPK10;GNG12;GABRG2
GABAergic synapse	GABRA4;SLC12A5;PRKACA;GABRB3;GAD2;GNAO1;PRKACB;GNG11;SLC6A13
Nicotine addiction	SLC17A8;GABRE;CHRNA6;GRIA3;GABRA6;GRIN2C;GABRB1;GABRB3;GRIN1

Gabra6 has several biochemical functions, for example, contributes_to GABA-A receptor activity, benzodiazepine receptor activity, chloride channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Gabra6 itself. We selected most functions Gabra6 had, and list some proteins which have the same functions with Gabra6. You can find most of the proteins on our site.

Function	Related Protein
contributes_to GABA-A receptor activity	GABRG1;GABRR2A;GABRG3;GABRA4;GABRA3;GABRR3A;GABRA2;GABRA5;GABRP
benzodiazepine receptor activity	GABRA6;GABRA4;GABRA3;GABRG2;TSPO;GABRA2
chloride channel activity	GABRE;GABRA4;GABRA1;SLC26A4;CLCN1;SLC26A6L;GABRA2;CLICA;CLIC6
inhibitory extracellular ligand-gated ion channel activity	GABRA6A;GABRA4;GABRA1;GABRA5;GABRG3;GABRA2;GABRA3;GABRA6;GABRG1

Gabra6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Gabra6 here. Most of them are supplied by our site. Hope this information will be useful for your research of Gabra6.

Ament, SA; Szelinger, S; et al. Rare variants in neuronal excitability genes influence risk for bipolar disorder. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:3576-3581(2015).

Srivastava, S; Cohen, J; et al. A Novel Variant in GABRB2 Associated with Intellectual Disability and Epilepsy. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 164A:2914-2921(2014).

GABA Receptors