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GALK1

  • Official Full Name

    galactokinase 1

  • Overview

    Galactokinase is a major enzyme for the metabolism of galactose and its deficiency causes congenital cataracts during infancy and presenile cataracts in the adult population.
  • Synonyms

    GALK1; galactokinase 1; GALK; galactokinase; EC 2.7.1.6; Galactose kinase; GALK 1; GALK1_HUMAN; GK1; GLK; GLK1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • GST
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GALK1-1156H Recombinant Human GALK1 protein, His&GST-tagged Insect Cells His/GST Met1-Leu392
Human GALK1-390H Recombinant Human Galactokinase 1, His-tagged E.coli His
Human GALK1-152H Recombinant Human GALK1 Protein, His-tagged E.coli His
Human GALK1-28117TH Recombinant Human GALK1, His-tagged E.coli His
Human GALK1-2504H Recombinant Human Galactokinase 1, His-tagged E.coli His 1-392aa
Human GALK1-28118TH Recombinant Human GALK1, His-tagged E.coli His 392 amino acids
Human GALK1-558HCL Recombinant Human GALK1 cell lysate Insect Cell N/A
Human GALK1-4681H Recombinant Human GALK1 Protein, GST-tagged Wheat Germ GST
Human GALK1-5227HF Recombinant Full Length Human GALK1 Protein, GST-tagged In Vitro Cell Free System GST 392 amino acids
Human GALK1-2327H Recombinant Human GALK1 Protein (Met1-Leu392), C-His tagged E.coli C-His Met1-Leu392
Human GALK1-1256H Recombinant Human GALK1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human GALK1-6423H Recombinant Human GALK1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse Galk1-3137M Recombinant Mouse Galk1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish GALK1-1521Z Recombinant Zebrafish GALK1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GALK1 Related Articles

GALK1 involved in several pathways and played different roles in them. We selected most pathways GALK1 participated on our site, such as Galactose metabolism, Amino sugar and nucleotide sugar metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GALK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Galactose metabolismaLA;PGM1;GALM;HKDC1;GALK1;UGP2A;G6PCA.2;PFKP;GALE
Amino sugar and nucleotide sugar metabolismGPR19;CHIA.4;HK1;GPIB;RENBP;CHIA.3;GFPT2;NANS;PGM1
Metabolic pathwaysCYP2P8;LIPG;MBOAT2;POLR2E;GCNT4A;GALNT18A;PAICS;Akr1b3;POLR3H

GALK1 has several biochemical functions, for example, ATP binding, galactokinase activity, galactose binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GALK1 itself. We selected most functions GALK1 had, and list some proteins which have the same functions with GALK1. You can find most of the proteins on our site.

Function Related Protein
ATP bindingTYRO3;ACLYA;CHD4A;LRRK1;HARS2;DNAJA2;SARS2;Fert2;KIF16B
galactokinase activityGALK2;GALK1
galactose bindingGALK1;COLEC12;LGALS9;ENG;CLEC4F

GALK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GALK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GALK1.

OTUD4; DMWD; 15-deoxy-delta(12,14; ESR1; VCAM1; CD9; AGO4

Chacon-Camacho, OF; Buentello-Volante, B; et al. Homozygosity mapping identifies a GALK1 mutation as the cause of autosomal recessive congenital cataracts in 4 adult siblings. GENE 534:218-221(2014).
Tomizawa, M; Shinozaki, F; et al. Survival of Primary Human Hepatocytes and Death of Induced Pluripotent Stem Cells in Media Lacking Glucose and Arginine. PLOS ONE 8:-(2013).
  • Q&As
  • Reviews

Q&As (6)

Ask a question
Are there different isoforms or variants of GALK1? 03/04/2022

Yes, there may be different subtypes or variants of GALK1 that may have different biological functions.

How do these different subtypes or variants function in cells? 03/18/2021

Different subtypes or variants may play different roles in cells, and the specific mechanisms need further research.

What are the effects of regulating GALK1 expression on cells? 03/16/2021

Regulating the expression of GALK1 may affect the glycolysis process and energy metabolism of cells.

What is the mechanism of action of these drugs? 12/28/2020

The mechanism of action of these drugs may include inhibition of GALK1 activity, regulation of its expression level, etc.

Is GALK1 involved in other biological processes? 08/01/2020

In addition to glycolysis, GALK1 may also be involved in other biological processes, such as cell signaling.

How to regulate the expression of GALK1 experimentally? 03/01/2020

The expression of GALK1 can be regulated by gene knockout, transgene and other technologies.

Customer Reviews (3)

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Reviews
09/06/2022

    The production process of GALK1 is stable and reliable, with high batch refolding.

    07/21/2022

      GALK1 is pure and has no other proteins or impurities.

      04/28/2021

        GALK1 has good stability in solution and is not easy to aggregate or deactivate.

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