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GALNT2

  • Official Full Name

    UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)

  • Overview

    This gene encodes polypeptide N-acetylgalactosaminyltransferase 2, a member of the GalNAc-transferases family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation in a cell is regulated by a repertoire of GalNAc-transferases.
  • Synonyms

    GALNT2; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2); polypeptide N-acetylgalactosaminyltransferase 2; GalNAc T2; GalNAc-T2; GALT2_HUMAN; GaNTase 2; Polypeptide GalNAc transferase 2; Polypeptide N acetylgalactosaminyltransferase 2 soluble form; Polypeptide N-acetylgalactosaminyltransferase 2 soluble form; pp GaNTase 2; pp-GaNTase 2; Protein UDP acetylgalactosaminyltransferase 2; Protein-UDP acetylgalactosaminyltransferase 2; UDP GalNAc transferase 2; UDP N acetyl alpha D galactosamine:polypeptide N acetylgalactosaminyltransferase 2; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 2; UDP-GalNAc transferase 2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Rhizobia
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Mammalian Cell
  • P. pastoris
  • Wheat Germ
  • Fc
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GALNT2-27303TH Recombinant Human GALNT2 Wheat Germ N/A 99 amino acids
Human GALNT2-13136H Recombinant Human GALNT2, His-tagged E.coli His 222-571a.a.
Human GALNT2-585H Recombinant Human GALNT2 Mammalian Cell His
Human GALNT2-229H Recombinant Human GALNT2, His tagged Human Cell Fc
Human GALNT2-907HCL Recombinant Human GALNT2 cell lysate Human Cell N/A
Human GALNT2-4698H Recombinant Human GALNT2 Protein P. pastoris N/A
Human GALNT2-1478H Recombinant Human GALNT2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human GALNT2-4699H Recombinant Human GALNT2 Protein, GST-tagged Wheat Germ GST
Human GALNT2-1252H Recombinant Human GALNT2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human GALNT2-3005H-B Recombinant Human GALNT2 Protein Pre-coupled Magnetic Beads HEK293
Human GALNT2-3005H Recombinant Human GALNT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human GALNT2-1265H Recombinant Human GALNT2 protein, His-tagged HEK293 His Lys52-Gln571
Mouse GALNT2-6185M Recombinant Mouse GALNT2 Protein Mammalian Cell His
Mouse Galnt2-366M Recombinant Mouse Galnt2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse GALNT2-3450M Recombinant Mouse GALNT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GALNT2-3450M-B Recombinant Mouse GALNT2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque GALNT2-1807R Recombinant Rhesus monkey GALNT2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque GALNT2-1628R-B Recombinant Rhesus Macaque GALNT2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque GALNT2-1628R Recombinant Rhesus Macaque GALNT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhizobia GALNT2-4700R Recombinant Rhizobia GALNT2 Protein E.coli N/A
Zebrafish GALNT2-6862Z Recombinant Zebrafish GALNT2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GALNT2 Related Articles

GALNT2 involved in several pathways and played different roles in them. We selected most pathways GALNT2 participated on our site, such as Mucin type O-Glycan biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GALNT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Mucin type O-Glycan biosynthesisC1GALT1C1;ST3GAL1;GALNT9;GCNT3;GALNT4;POC1B-GALNT4;GCNT4A;GALNT10;GALNT6
Metabolic pathwaysFDFT1;CMPK2;PTGDS;UQCRQ;PMM2;OLAH;ACSM5;ALG6;CMPK1

GALNT2 has several biochemical functions, for example, carbohydrate binding, manganese ion binding, polypeptide N-acetylgalactosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GALNT2 itself. We selected most functions GALNT2 had, and list some proteins which have the same functions with GALNT2. You can find most of the proteins on our site.

Function Related Protein
carbohydrate bindingILLR1;REG3A;KLRF1;GALM;LGALS2B;CHI3L1;CD55;LGALS2;PRG3
manganese ion bindingMTPAP;IMPA1;PIM1;PPM1AB;PRIMPOL;GALNT1;FEN1;ENDOU;TDP2
polypeptide N-acetylgalactosaminyltransferase activityGALNT10;GALNTL1;GALNT5;GALNT1;GALNT4;GALNT11;GALNT6;C1GALT1C1;GALNT9
protein bindingMAPK13;AGBL4;YWHAH;MKI67IP;PRSS2;BBS4;C1orf50;LRP12;RAMP1

GALNT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GALNT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GALNT2.

CCDC155; NOD2; AP4M1; Shoc2; Itgb1; PTPN1; Rab5c; Rad54l; REEP5; Papss1; MMGT1; Tor1aip1; Hspa14; Mis12; AP4S1; Uso1

Ho, WL; Chou, CH; et al. GALNT2 suppresses malignant phenotypes through IGF-1 receptor and predicts favorable prognosis in neuroblastoma. ONCOTARGET 5:12247-12259(2014).
Cole, CB; Nikpay, M; et al. Adiposity significantly modifies genetic risk for dyslipidemia. JOURNAL OF LIPID RESEARCH 55:2416-2422(2014).
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