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GINS4

  • Official Full Name

    GINS complex subunit 4

  • Overview

    SLD5 or GINS4 is a member of the GINS complex which is involved in initiation of replication and unwinding of DNA. It is highly conserved amongst eukaryotes. The GINS complex in yeast associates with DNA polymerase epsilon and stimulates its catalytic activity. It also interacts with Cdc45 and the MCM2-7 complex to activate the eukaryotic minichromosome maintenance helicase.
  • Synonyms

    GINS complex subunit 4; GINS4; SLD5 homolog; SLD5; MGC14799; GINS complex subunit 4 (Sld5 homolog); 2810037C03Rik; 4933405K01Rik; DNA replication complex GINS protein SLD5;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GINS4-353H Recombinant Human GINS complex subunit 4 (Sld5 homolog), His-tagged E.coli His
Human GINS4-5931HCL Recombinant Human GINS4 293 Cell Lysate HEK293 N/A
Human GINS4-4910H Recombinant Human GINS4 Protein, GST-tagged Wheat Germ GST
Human GINS4-6300H Recombinant Human GINS4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human GINS4-5265HF Recombinant Full Length Human GINS4 Protein, GST-tagged In Vitro Cell Free System GST 223 amino acids
Mouse GINS4-6361M Recombinant Mouse GINS4 Protein Mammalian Cell His
Mouse GINS4-3563M Recombinant Mouse GINS4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Gins4-405M Recombinant Mouse Gins4 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse GINS4-3563M-B Recombinant Mouse GINS4 Protein Pre-coupled Magnetic Beads HEK293
Rat GINS4-2539R Recombinant Rat GINS4 Protein Mammalian Cell His
Rat GINS4-2195R-B Recombinant Rat GINS4 Protein Pre-coupled Magnetic Beads HEK293
Rat GINS4-2195R Recombinant Rat GINS4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque GINS4-1854R Recombinant Rhesus monkey GINS4 Protein, His-tagged Mammalian Cell His
Rhesus Macaque GINS4-1674R-B Recombinant Rhesus Macaque GINS4 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque GINS4-1674R Recombinant Rhesus Macaque GINS4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish GINS4-980Z Recombinant Zebrafish GINS4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

GINS4 involved in several pathways and played different roles in them. We selected most pathways GINS4 participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, DNA Replication, which may be useful for your reference. Also, other proteins which involved in the same pathway with GINS4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell CycleNCAPD3;CLASP1;TMPO;CDK2;SMC1B;MAPRE1;PCNA;ESPL1;MCM3
Cell Cycle, MitoticB9D2;NUDC;H3F3B.1;CEP78;CENPP;LIN37;TUBB4B;NCAPD3;STAG2
DNA ReplicationMCM10;POLE2;rnhA;RFC4;POLD2;GINS3;GINS1;RNASEH2B;RPA3
DNA strand elongationDNA2;GINS4;GINS2;GINS1;GINS3
S PhaseESCO1;GINS3;GINS4;ESCO2;GINS2;MYCA;GINS1
Synthesis of DNAGINS2;GINS4;GINS1;GINS3
Unwinding of DNAGINS4;GINS1;GINS2;GINS3

GINS4 has several biochemical functions, for example, contributes_to 3-5 DNA helicase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GINS4 itself. We selected most functions GINS4 had, and list some proteins which have the same functions with GINS4. You can find most of the proteins on our site.

Function Related Protein
contributes_to 3-5 DNA helicase activityGINS2;GINS4
protein bindingRB1CC1;POU2F1;KCNA1;TRPV4;GOPC;EDC3;COG7;POR;PFN2

GINS4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GINS4 here. Most of them are supplied by our site. Hope this information will be useful for your research of GINS4.

GINS2; MCMBP; RPA2; RPA1; RPA3; Clspn; Tipin; Timeless

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