GPC5
-
Official Full Name
glypican 5
-
Overview
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage.These proteins may play a role in the control of cell division and growth regulation. -
Synonyms
GPC5; glypican 5; glypican-5; glypican proteoglycan 5; Glypican 5 precursor; GPC5_HUMAN; Secreted glypican-5; bA93M14.1; OTTHUMP00000018551;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Insect Cell
- Insect Cells
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- C
- His
- GST
- His (Fc)
- Avi
- His|T7
- Myc
- DDK
- MYC
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- GPC5 Related Articles
GPC5 involved in several pathways and played different roles in them. We selected most pathways GPC5 participated on our site, such as A tetrasaccharide linker sequence is required for GAG synthesis, Chondroitin sulfate/dermatan sulfate metabolism, Defective B3GALT6 causes EDSP2 and SEMDJL1, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPC5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| A tetrasaccharide linker sequence is required for GAG synthesis | GPC5;BGNB;BGN;BCAN;GPC6;NCAN;GPC1B;VCANB;GPC1A |
| Chondroitin sulfate/dermatan sulfate metabolism | GPC1B;BGNB;AGRN;NCAN;VCANB;BCAN;BGNA;UST;CSPG4 |
| Defective B3GALT6 causes EDSP2 and SEMDJL1 | NCAN;CSPG4;VCAN;DCN;BGN;GPC5;AGRN;CSPG5;GPC6 |
| Defective B3GAT3 causes JDSSDHD | GPC5;BCAN;VCAN;NCAN;BGN;CSPG4;DCN;CSPG5;AGRN |
| Defective B4GALT7 causes EDS, progeroid type | BCAN;GPC6;DCN;GPC5;NCAN;CSPG5;AGRN;VCAN;CSPG4 |
| Defective EXT1 causes exostoses 1, TRPS2 and CHDS | GPC5;AGRN;GPC6 |
| Defective EXT2 causes exostoses 2 | GPC6;GPC5;AGRN |
| Disease | SFTPC;VPS37A;HEY1;OPN1LW;MTRR;PRELP;AP2A2;OPN1SW;TLR10 |
GPC5 has several biochemical functions, for example, heparan sulfate proteoglycan binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GPC5 itself. We selected most functions GPC5 had, and list some proteins which have the same functions with GPC5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| heparan sulfate proteoglycan binding | Gpc2;GPC1B;GPC6A;GPC3;HRG;HPSE2;AGRN;SEMA5A;GPC1 |
GPC5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GPC5 here. Most of them are supplied by our site. Hope this information will be useful for your research of GPC5.
Shcbp1; DCPS
- Q&As
- Reviews
Q&As (5)
Ask a questionGPC5 is closely associated with studies of lung, gastric and liver cancers.
Overexpression of GPC5 inhibits tumor cell proliferation, invasion and metastasis.
GPC5 is lowly expressed in lung cancer tissues.
GPC5 is localized on the outer surface of the plasma membrane.
GPC5 is involved in the regulation of cell proliferation, differentiation, adhesion and migration.
Customer Reviews (3)
Write a reviewThe staff had a good attitude, actively communicated with me and solved many technical problems.
The GPC5 proteins purchased from your company is suitable for WB.
The technician modified my experimental protocol so that my experiment went smoothly.
Ask a Question for All GPC5 Products
Required fields are marked with *
My Review for All GPC5 Products
Required fields are marked with *
