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GTSE1

Official Full Name

G-2 and S-phase expressed 1
Overview

The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.
Synonyms

GTSE1; G-2 and S-phase expressed 1; G2 and S phase-expressed protein 1; B99; GTSE 1; B99 homolog; G 2 and S phase expressed 1; G two S phase expressed protein 1; protein B99 homolog;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	GTSE1-4479H	Recombinant Human GTSE1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	GTSE1-5680HCL	Recombinant Human GTSE1 293 Cell Lysate	HEK293	N/A		Inquiry
Human	GTSE1-3338HF	Recombinant Full Length Human GTSE1 Protein, GST-tagged	In Vitro Cell Free System	GST	720 amino acids	Inquiry
Zebrafish	GTSE1-2800Z	Recombinant Zebrafish GTSE1	Mammalian Cell	His		Inquiry
Chicken	GTSE1-2986C	Recombinant Chicken GTSE1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
GTSE1 Related Articles

GTSE1 involved in several pathways and played different roles in them. We selected most pathways GTSE1 participated on our site, such as p signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with GTSE1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
p signaling pathway	ATM;RRM2B;CCNB1;BBC3;PERP;CCNB2;EI24;CCND2;CCNE2

GTSE1 has several biochemical functions, for example, molecular_function, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GTSE1 itself. We selected most functions GTSE1 had, and list some proteins which have the same functions with GTSE1. You can find most of the proteins on our site.

Function	Related Protein
molecular_function	SLC15A5;FAM184A;NLRP4B;CDCA7A;TAS2R110;TM9SF2;GM4070;MARCH11;XRRA1
protein binding	THOC4;GNB1B;DUSP26;RFX3;PMEPA1;UBXN8;ACVR1L;STX4;KBTBD6

GTSE1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GTSE1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GTSE1.

PLK1; USP11; HIP1; SEC23A; Sec24c; PICALM; SEC16A; SYNJ1; HIP1; PIK3C2A; GAK; SEC16A; SEC16A; N4BP3

Munzer, DGG; Kostoglou, M; et al. Developing a cyclin blueprint as a tool for mapping the cell cycle in GS-NSO. BIOCHEMICAL ENGINEERING JOURNAL 81:97-107(2013).

Kastner, S; Voss, T; et al. Expression of G Protein-Coupled Receptor 19 in Human Lung Cancer Cells Is Triggered by Entry into S-Phase and Supports G(2)-M Cell-Cycle Progression. MOLECULAR CANCER RESEARCH 10:1343-1358(2012).