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GUCA2B

  • Official Full Name

    guanylate cyclase activator 2B (uroguanylin)

  • Overview

    Uroguanylin is a 16 amino acid peptide that is secreted by enterochromaffin cells in the duodenum and proximal small intestine. Guanylin acts as an agonist of the guanylyl cyclase receptor GC-C and regulates electrolyte and water transport in intestinal and renal epithelia.
  • Synonyms

    GUCA2B; guanylate cyclase activator 2B (uroguanylin); UGN; GCAP-II; Guanylate cyclase activator 2B; Guanylate cyclase C-activating peptide 2; Guanylate cyclase C-activating peptide II; Uroguanylin; OTTHUMP00000007927;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Yeast
  • C
  • Myc
  • DDK
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • MYC
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GUCA2B-3706H Recombinant Human GUCA2B E.coli N/A
Human GUCA2B-127H Recombinant Human Guanylate Cyclase Activator 2B (Uroguanylin) E.coli N/A
Human GUCA2B-767HCL Recombinant Human GUCA2B cell lysate N/A
Human GUCA2B-1650H Recombinant Human GUCA2B Protein (27-112 aa), His-tagged Yeast His 27-112 aa
Human GUCA2B-5098H Recombinant Human GUCA2B protein, His-tagged HEK293 His 27-112aa
Human GUCA2B-368H Recombinant Human GUCA2B Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human GUCA2B-2547H Recombinant Human GUCA2B Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human GUCA2B-4375H Recombinant Human GUCA2B protein, His-SUMO-tagged E.coli His-SUMO 27-112aa
Human GUCA2B-2224H Recombinant Human GUCA2B Protein, His-tagged E.coli N-His Val27-Leu112
Mouse GUCA2B-7386M Recombinant Mouse GUCA2B Protein Mammalian Cell His
Mouse GUCA2B-4008M Recombinant Mouse GUCA2B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse GUCA2B-544M Recombinant Mouse GUCA2B Protein (22-106 aa), GST-tagged E.coli GST 22-106 aa
Mouse GUCA2B-657M Recombinant Mouse GUCA2B protein, His-tagged(VLPs) HEK293 His Met1-Met433
Mouse GUCA2B-4008M-B Recombinant Mouse GUCA2B Protein Pre-coupled Magnetic Beads HEK293
Mouse GUCA2B-1407M Recombinant Mouse GUCA2B Protein (22-106 aa), His-tagged Yeast His 22-106 aa
Mouse Guca2b-1078M Recombinant Mouse Guca2b Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse Guca2b-1606M Recombinant Mouse Guca2b Protein, His-tagged E.coli N-His Val22-Cys106
Rat GUCA2B-2753R Recombinant Rat GUCA2B Protein Mammalian Cell His
Rat Guca2b-1607R Recombinant Rat Guca2b Protein, His-tagged E.coli N-His Val22-Cys106
Rat GUCA2B-2407R Recombinant Rat GUCA2B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GUCA2B-2407R-B Recombinant Rat GUCA2B Protein Pre-coupled Magnetic Beads HEK293
Chicken GUCA2B-4160C Recombinant Chicken GUCA2B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GUCA2B Related Articles

GUCA2B involved in several pathways and played different roles in them. We selected most pathways GUCA2B participated on our site, such as Myometrial Relaxation and Contraction Pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GUCA2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Myometrial Relaxation and Contraction PathwaysRGS20;RGS18;GABPA;CNN1;RGS6;RGS11;RGS19;RGS14;IGFBP6

GUCA2B has several biochemical functions, for example, calcium sensitive guanylate cyclase activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GUCA2B itself. We selected most functions GUCA2B had, and list some proteins which have the same functions with GUCA2B. You can find most of the proteins on our site.

Function Related Protein
calcium sensitive guanylate cyclase activator activityGUCA1C;GUCA1E;RCVRN;GUCA1A;GUCA1D;GUCA2B;GUCA1G;GUCA1B

GUCA2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GUCA2B here. Most of them are supplied by our site. Hope this information will be useful for your research of GUCA2B.

Tain, YL; Lee, CT; et al. Long-Term Effects of Maternal Citrulline Supplementation on Renal Transcriptome Prevention of Nitric Oxide Depletion-Related Programmed Hypertension: The Impact of Gene-Nutrient Interactions. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 15:23255-23268(2014).
Camilleri, M; Carlson, P; et al. RNA sequencing shows transcriptomic changes in rectosigmoid mucosa in patients with irritable bowel syndrome-diarrhea: a pilot case-control study. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 306:C1089-C1098(2014).
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