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H2-Aa

  • Official Full Name

    histocompatibility 2, class II antigen A, alpha

  • Synonyms

    H2-AA;histocompatibility 2, class II antigen A, alpha;ENSMUSG00000036594;Ia1;H2Aa;Ia-1;H-2Aa;Aalpha;IAalpha;I-Aalpha;17 B1;17 18.65 cM;histocompatibility 2, class II antigen A, alpha;histocompatibility 2, class II antigen A, alpha;A alpha;MHC-II I-A(d) alpha;MHC class II antigen;major histocompatibility protein class II alpha chain;H-2 class II histocompatibility antigen, A-B alpha chain;H-2 class II histocompatibility antigen, A-F alpha chain;H-2 class II histocompatibility antigen, A-K alpha chain;H-2 class II histocompatibility antigen, A-Q alpha chain;H-2 class II histocompatibility antigen, A-R alpha chain;H-2 class II histocompatibility antigen, A-S alpha chain;H-2 class II histocompatibility antigen, A-U alpha chain;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Mouse H2-AA-7424M Recombinant Mouse H2-AA Protein Mammalian Cell His
Mouse H2-Aa-1084M Recombinant Mouse H2-Aa Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse H2-AA-4038M Recombinant Mouse H2-AA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse H2-AA-4038M-B Recombinant Mouse H2-AA Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • H2-Aa Related Articles

H2-Aa involved in several pathways and played different roles in them. We selected most pathways H2-Aa participated on our site, such as Phagosome, Cell adhesion molecules (CAMs), Antigen processing and presentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with H2-Aa were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
PhagosomeRAB5C;RAC1;ATP6V0A4;ATP6V1F;ATP6V0D1;RAB7B;HLA-DRB1;RAB7A;SEC61AL2
Cell adhesion molecules (CAMs)CLDN10A;CADM1A;LRRC4C;H2-Q10;CLDNK;ITGB7;HLA-DRA;ITGA6B;MPZ
Antigen processing and presentationKIR2DS4;H2-AB1;HLA-DRB1;HSPA5;IFI30;HLA-E;LGMN;HLA-DOA;NFYC
Intestinal iHLA-DRB4;CCL25;TGFB1A;BLB2;HLA-DPB1;IL6;HLA-DRB3;MAP3K14;PIGR
ne network for IgA productionH2-AB1;CXCL12B;HLA-DPA1;CCL27B;MHC2A;IL6;IL5;HLA-DQA1;ITGA4
Type I diabetes mellitusPRF1;HLA-DRB5;HLA-DQA1;HLA-DOB;IL1B;Il2;HLA-DRB1;GAD2;HLA-E
LeishmaniasisITGB2;FCGR1;NCF2;IRAK4;IRAK1;PTPN6;NFKBIA;HLA-DOA;FOS
ToxoplasmosisIRAK4;MAPK3;PPIF;ALOX5;CASP9;BIRC8;H2-AA;PIK3R3;IRGM1
Staphylococcus aureus infectionFPR1;H2-AB1;C1R;HLA-DQA2;FCGR2C;SELPLG;FPR2;H2-AA;FGG
TuberculosisCALM3;FCGR2A;MAPK3;MAPK1;IFNA21;BID;ITGAM;IFNA17;IFNA10
Influenza ATNFRSF1A;LOC100686744;IL8L1;MX1;IFIH1;IFNGR1;NXT2;AKT1;IFNB1
HTLV-I infectionETS1;WNT5A;HLA-C;NFKB2;RRAS2;LTA;ITGB2;MAP3K1;SPI1
Herpes simplex infectionTTC6;NXF2;TNF;TNFRSF14;FADD;MHC2DCB;IRF7;SRSF5A;IFNA3
AsthmaIL9;HLA-DRB1;H2-AA;HLA-DRB4;HLA-DRA;FCER1A;IL4;HLA-DPA1;HLA-DQB1
AutoiIFNA8;IFNA16;IFNA21;Fasl;HLA-DOA;HLA-DQA2;H2-AB1;PRF1;GZMB
ne thyroid diseaseCD40;HLA-F;HLA-DRA;FAS;HLA-B;IFNA4;IFNA13;HLA-DOB;HLA-DRB4
Inflammatory bowel disease (IBD)HLA-DMB;IL6;IL12RB1;IL18R1;IL22;IL23;HLA-DRA;IL21R;STAT3
Systemic lupus erythematosusH2AFJ;TRIM21;C6;HIST1H4J;C1QC;FCGR3;HIST1H2BM;FCGR1;SNRPD3
Rheumatoid arthritisTNFSF13B;ATP6V1C1;Il23a;FLT1;ATP6V0E;ATP6V1B2;TLR2;CXCL5;ATP6V1A
Allograft rejectionIL4;HLA-DMA;GZMB;IL12A;HLA-B;HLA-DRB4;HLA-DRB1;FAS;TNF
Graft-versus-host diseaseKIR2DL3;FAS;PRF1;IL1B;IFNG;KLRC1;KIR2DL1;HLA-DRB1;HLA-DQB1
Viral myocarditisHLA-DQA1;HLA-DRB5;BID;ICAM1;Casp3;EIF4G3;ABL2;HLA-DQB1;HLA-DPA1

H2-Aa has several biochemical functions, for example, peptide antigen binding, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by H2-Aa itself. We selected most functions H2-Aa had, and list some proteins which have the same functions with H2-Aa. You can find most of the proteins on our site.

Function Related Protein
peptide antigen bindingH2-Q10;BF2;HLA-F;MHC1ZDA;TUBB3;MHC1UDA;CLEC4M;HLA-DRB1;HLA-DRB5
protein bindingCTR9;C7orf53;STAM2;HIST1H2BB;DLGAP4;SIRT3;TSSK2;MAT2A;PRMT1
protein heterodimerization activityDMRT3A;SCUBE1;HIST1H2BL;HIST3H2BB;MAP3K7;NR4A2;HYPM;CAPN2;H2BFWT

H2-Aa has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with H2-Aa here. Most of them are supplied by our site. Hope this information will be useful for your research of H2-Aa.

H2-Ab1

Zemelka-Wiacek, M; Szczepanik, M; et al. Tc1-mediated contact sensitivity reaction, its mechanism and regulation. POSTEPY HIGIENY I MEDYCYNY DOSWIADCZALNEJ 68:955-969(2014).
Schwaiger, J; Aberle, JH; et al. Specificities of Human CD4(+) T Cell Responses to an Inactivated Flavivirus Vaccine and Infection: Correlation with Structure and Epitope Prediction. JOURNAL OF VIROLOGY 88:7828-7842(2014).
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