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HABP2

  • Official Full Name

    hyaluronan binding protein 2

  • Overview

    The protein encoded by this gene is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. The encoded protein is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This protease is known to cleave urinary plasminogen activator, coagulation factor VII, and the alpha and beta chains of fibrinogen, but not prothrombin, plasminogen, or the gamma chain of fibrinogen. Two transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    HABP2; hyaluronan binding protein 2; hyaluronan-binding protein 2; factor VII activating protein; FSAP; HABP; HGFAL; PHBP; plasma hyaluronan binding protein; Factor seven activating protease; Factor seven-activating protease; Factor VII-activating protease; HABP 2; HABP2_HUMAN; Hepatocyte growth factor activator like protein; Hepatocyte growth factor activator-like protein; Hyaluronan-binding protein 2 27 kDa light chain alternate form; Hyaluronic acid binding protein 2; Plasma hyaluronan-binding protein; OTTHUMP00000020505; hepatocyte;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • SUMO
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HABP2-4549H Recombinant Human HABP2 Protein, GST-tagged Wheat Germ GST
Human HABP2-20H Recombinant Human HABP2 protein, GST-tagged E.coli GST C-term-389aa
Human HABP2-28753TH Recombinant Human HABP2 Wheat Germ N/A 100 amino acids
Human HABP2-21H Recombinant Human HABP2 protein, His-tagged HEK293 His
Human HABP2-7850H Recombinant Human HABP2 protein, His-tagged E.coli His Phe24~Phe560
Human HABP2-5649HCL Recombinant Human HABP2 293 Cell Lysate HEK293 N/A
Human HABP2-4391H Recombinant Human HABP2 protein, His-SUMO-tagged E.coli His-SUMO 37-313aa
Human HABP2-4392H Recombinant Human HABP2 protein, His-SUMO-tagged E.coli His-SUMO 314-560aa
Human HABP2-2860H Recombinant Human HABP2 Protein (Met1-Gln279), C-His tagged Mammalian cells C-His Met1-Gln279
Human HABP2-3418HF Recombinant Full Length Human HABP2 Protein, GST-tagged In Vitro Cell Free System GST 560 amino acids
Human HABP2-2861H Recombinant Human HABP2 Protein (Ser25-Phe560), N-His tagged E.coli N-His Ser25-Phe560
Rat HABP2-2779R Recombinant Rat HABP2 Protein Mammalian Cell His
Rat HABP2-2433R Recombinant Rat HABP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat HABP2-2433R-B Recombinant Rat HABP2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish HABP2-6142Z Recombinant Zebrafish HABP2 Mammalian Cell His
Chicken HABP2-4792C Recombinant Chicken HABP2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HABP2 Related Articles
  • HABP2 Related Research Area

HABP2 involved in several pathways and played different roles in them. We selected most pathways HABP2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HABP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

HABP2 has several biochemical functions, for example, glycosaminoglycan binding, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HABP2 itself. We selected most functions HABP2 had, and list some proteins which have the same functions with HABP2. You can find most of the proteins on our site.

Function Related Protein
glycosaminoglycan bindingEGFLAM;BGN;VCAN;SERPINE2;ENG;Shh;TGFBR3;TGFBR2;EPYC
serine-type endopeptidase activityKLK1;Prss32;KLK5;FURINA;HTRA1;PRSS23;F9B;CTRB1;PIK3IP1

HABP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HABP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HABP2.

PARP2

Iida, J; Dorchak, J; et al. Role for chondroitin sulfate glycosaminoglycan in NEDD9-mediated breast cancer cell growth. EXPERIMENTAL CELL RESEARCH 330:358-370(2015).
Arif, M; Thakur, SC; et al. Disrupted hyaluronan binding protein 1 (HABP1) expression: one of the key mediator for ovarian dysfunction in polycystic ovary rat. MOLECULAR AND CELLULAR BIOCHEMISTRY 398:233-244(2015).
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