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HAGH

  • Official Full Name

    hydroxyacylglutathione hydrolase

  • Overview

    The enzyme encoded by this gene is classified as a thiolesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. Two transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    HAGH; hydroxyacylglutathione hydrolase; hydroxyacyl glutathione hydrolase; hydroxyacylglutathione hydrolase, mitochondrial; GLO2; GLXII; HAGH1; GLX II; Glyoxalase II; OTTHUMP00000158839; OTTHUMP00000158840; hydroxyacylglutathione hydroxylase; GLX2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HAGH-1799H Recombinant Human HAGH protein, His-tagged E.coli His Met1-Asp260
Human HAGH-4559H Recombinant Human HAGH Protein, GST-tagged Wheat Germ GST
Human HAGH-932H Recombinant Human Hydroxyacylglutathione Hydrolase, His-tagged E.coli His
Human HAGH-163H Recombinant Human HAGH protein, T7-tagged E.coli T7
Human HAGH-828H Recombinant Human Hydroxyacylglutathione Hydrolase, T7-tagged E.coli T7
Human HAGH-5644HCL Recombinant Human HAGH 293 Cell Lysate HEK293 N/A
Human HAGH-1787H Recombinant Human HAGH protein, GST-tagged E.coli GST 1-260 aa
Human HAGH-6076H Recombinant Human HAGH Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HAGH-5267H Recombinant Human HAGH protein, GST-tagged E.coli GST 50-308aa
Human HAGH-3448HF Recombinant Full Length Human HAGH Protein, GST-tagged In Vitro Cell Free System GST 260 amino acids
Human HAGH-2227H Recombinant Human HAGH Protein, His-tagged E.coli N-His Met1-Asp308
Human HAGH-2672H Recombinant Human HAGH Protein (Met49-Ile254), N-His tagged E.coli N-His Met49-Ile254
Mouse HAGH-7470M Recombinant Mouse HAGH Protein Mammalian Cell His
Mouse Hagh-1614M Recombinant Mouse Hagh Protein, His-tagged E.coli N-His Met1-Asp309
Mouse HAGH-4053M Recombinant Mouse HAGH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse HAGH-4053M-B Recombinant Mouse HAGH Protein Pre-coupled Magnetic Beads HEK293
Mouse Hagh-3352M Recombinant Mouse Hagh Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat HAGH-2784R Recombinant Rat HAGH Protein Mammalian Cell His
Rat HAGH-2438R-B Recombinant Rat HAGH Protein Pre-coupled Magnetic Beads HEK293
Rat HAGH-2438R Recombinant Rat HAGH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey HAGH-584C Recombinant Cynomolgus HAGH Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey HAGH-330C Recombinant Cynomolgus Monkey HAGH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey HAGH-330C-B Recombinant Cynomolgus Monkey HAGH Protein Pre-coupled Magnetic Beads HEK293
Zebrafish HAGH-10398Z Recombinant Zebrafish HAGH Mammalian Cell His
Chicken HAGH-2018C Recombinant Chicken HAGH Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HAGH Related Articles

HAGH involved in several pathways and played different roles in them. We selected most pathways HAGH participated on our site, such as Pyruvate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with HAGH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Pyruvate metabolismPCK1;ALDH2.2;PDPR;SLC16A8;MDH1AA;FH1;PDHA1B;PDHB;ACAT2

HAGH has several biochemical functions, for example, hydroxyacylglutathione hydrolase activity, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HAGH itself. We selected most functions HAGH had, and list some proteins which have the same functions with HAGH. You can find most of the proteins on our site.

Function Related Protein
hydroxyacylglutathione hydrolase activityPNKD;HAGH
metal ion bindingDTX1;MB;PRDM10;NFS1;NAIP1;GNAS;ZNF32;CNDP2;NME6
protein bindingASPA;TSGA10IP;RFWD3;DTNB;DPH2;P2RY1;NR1H2;TRIP10;ACTL7A

HAGH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HAGH here. Most of them are supplied by our site. Hope this information will be useful for your research of HAGH.

TERF2IP; BST2

Kovac, J; Podkrajsek, KT; et al. Weak association of glyoxalase 1 (GLO1) variants with autism spectrum disorder. EUROPEAN CHILD & ADOLESCENT PSYCHIATRY 24:75-82(2015).
Rabbani, N; Xue, MZ; et al. Activity, regulation, copy number and function in the glyoxalase system. BIOCHEMICAL SOCIETY TRANSACTIONS 42:419-424(2014).
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