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GSG2

  • Official Full Name

    germ cell associated 2 (haspin)

  • Overview

    Required for normal alignment of chromosomes at metaphase. Phosphorylates histone H3 'Thr-3' during mitosis.
  • Synonyms

    GSG2; germ cell associated 2 (haspin); HASPIN; serine/threonine-protein kinase haspin; H-haspin; germ cell-specific gene 2 protein; haploid germ cell-specific nuclear protein kinase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • HEK293
  • Insect (sf21)
  • Mammalian Cell
  • Sf9 Insect Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GSG2-1586H Recombinant Human Germ Cell Associated 2 (haspin), GST-tagged Sf9 Insect Cell GST
Human GSG2-29180TH Recombinant Human GSG2 Sf9 Insect Cell N/A 329 amino acids
Human GSG2-756HCL Recombinant Human GSG2 cell lysate N/A
Human GSG2-4493HF Active Recombinant Full Length Human GSG2 Protein, GST-tagged Insect (sf21) GST 1-798
Mouse GSG2-7316M Recombinant Mouse GSG2 Protein Mammalian Cell His
Mouse GSG2-3961M-B Recombinant Mouse GSG2 Protein Pre-coupled Magnetic Beads HEK293
Mouse GSG2-3961M Recombinant Mouse GSG2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • GSG2 Related Articles
  • GSG2 Related Research Area

GSG2 involved in several pathways and played different roles in them. We selected most pathways GSG2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with GSG2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

GSG2 has several biochemical functions, for example, ATP binding, histone kinase activity (H3-T3 specific), protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GSG2 itself. We selected most functions GSG2 had, and list some proteins which have the same functions with GSG2. You can find most of the proteins on our site.

Function Related Protein
ATP bindingDGKA;STK26;KIF11;ABCC2;RAF1;STK4;FARSA;XRCC5;CAMK2G
histone kinase activity (H3-T3 specific)VRK1;GSG2
protein bindingTSSK4;AAGAB;EVI5;ECT2;CTNNBL1;LHX4;PCNA;GYS1;HSPBAP1
protein kinase activityRBM4.3;FASTKD3;CSNK1G2A;CSNK1D;PRKCBB;PDK1;GM4922;ARAF;CAMK1GA

GSG2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSG2 here. Most of them are supplied by our site. Hope this information will be useful for your research of GSG2.

HSP90AB1; H3F3A; KPNA6; MYC; MATR3; FBXL6; THAP11; EHMT1; HERC5

Sato, S; Maeda, C; et al. DNA Methylation-dependent Modulator of Gsg2/Haspin Gene Expression. JOURNAL OF REPRODUCTION AND DEVELOPMENT 57:526-533(2011).
Gohbara, A; Katagiri, K; et al. In Vitro Murine Spermatogenesis in an Organ Culture System. BIOLOGY OF REPRODUCTION 83:261-267(2010).
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