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HBD

  • Official Full Name

    HBD hemoglobin, delta [ Homo sapiens ]

  • Overview

    The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3% of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5-epsilon--Ggamma--Agamma--delta--beta-3. Mutations in the delta-globin gene are associated with beta-thalassemia.
  • Synonyms

    hemoglobin, delta; 4829; Ensembl:ENSG00000223609; hemoglobin subunit delta; delta globin; delta-globin chain; hemoglobin delta chain;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • E.coli
  • HEK293
  • GST
  • His
  • His|GST
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HBD-13680H Recombinant Human HBD, GST-tagged E.coli GST 1-147a.a.
Human HBD-7861H Recombinant Human HBD protein, His & GST-tagged E.coli His/GST Met1~Ala143 (Accession # P02042)
Human HBD-5621HCL Recombinant Human HBD 293 Cell Lysate HEK293 N/A
Human HBD-2443H Recombinant Human HBD Protein (Met1-Ala143), N-GST tagged E.coli N-GST Met1-Ala143
Human HBD-1060H Recombinant Human HBD Protein, His-tagged E.coli His
Human HBD-4296H Recombinant Human HBD protein, His-GST-tagged E.coli His/GST 2-147aa
  • Involved Pathway
  • Protein Function
  • Interacting Protein

HBD involved in several pathways and played different roles in them. We selected most pathways HBD participated on our site, such as Factors involved in megakaryocyte development and platelet production, Hemostasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HBD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Factors involved in megakaryocyte development and platelet productionIRF1B;GATA1;GATA2;KIF11;HBB-Y;H3F3D;HBG2;H3F3B.1;KIFC1
HemostasisMGC173646;MERTK;KIF15;PDE10A;KIFAP3;DGKQ;GATA2;CFHL2;S100A10B

HBD has several biochemical functions, for example, heme binding, iron ion binding, oxygen binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HBD itself. We selected most functions HBD had, and list some proteins which have the same functions with HBD. You can find most of the proteins on our site.

Function Related Protein
heme bindingCYGB;HBA-X;CYP11B2;CYP7A1;CYP2P8;HBQ1;CYP2X7;CYP3C4;CYP1A4
iron ion bindingTPH1;CYP8B2;BRSK2;TYW1B;MSMO1;NFU1;HBBE1.1;HBG1;CYP7A1A
oxygen bindingCYP2AA12;CYP2F2;CYP2P7;CYP19A1;CYP2P6;CYP2B19;CYP2C9;CYP2A13;CYP2C54
oxygen transporter activityHBB-BH1;HBZ;HBE1;HBA1;XGB;IPCEF1;HBG1;HBB-Y;CYGB2
protein bindingFN1;HOXD12;TMPRSS2;STXBP4;RALBP1;Cd24a;PAGE1;STOX1;EIF2A

HBD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HBD here. Most of them are supplied by our site. Hope this information will be useful for your research of HBD.

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