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HCFC2

  • Official Full Name

    host cell factor C2

  • Overview

    This gene encodes one of two proteins which interact with VP16, a herpes simplex virus protein that initiates virus infection. Both the encoded protein and the original Herpes host cell factor interact with VP16 through a beta-propeller domain. The original Herpes host cell factor, however, is effective at initiating viral infection while the encoded protein is not. Transcripts of varying length due to alternative polyadenylation signals have been described.
  • Synonyms

    HCFC2; host cell factor C2; host cell factor 2; HCF 2; C2 factor; HCF2; HCF-2; FLJ94012;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HCFC2-4619H Recombinant Human HCFC2 Protein, GST-tagged Wheat Germ GST
Human HCFC2-5612HCL Recombinant Human HCFC2 293 Cell Lysate HEK293 N/A
Human HCFC2-3506HF Recombinant Full Length Human HCFC2 Protein, GST-tagged In Vitro Cell Free System GST 792 amino acids
Human HCFC2-2233H Recombinant Human HCFC2 Protein, His-tagged E.coli N-His Phe677-Lys787
Rat HCFC2-2804R Recombinant Rat HCFC2 Protein Mammalian Cell His
Rat HCFC2-2459R Recombinant Rat HCFC2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat HCFC2-2459R-B Recombinant Rat HCFC2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque HCFC2-2049R Recombinant Rhesus monkey HCFC2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque HCFC2-1870R Recombinant Rhesus Macaque HCFC2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque HCFC2-1870R-B Recombinant Rhesus Macaque HCFC2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish HCFC2-2464Z Recombinant Zebrafish HCFC2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HCFC2 Related Articles

HCFC2 involved in several pathways and played different roles in them. We selected most pathways HCFC2 participated on our site, such as Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with HCFC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Herpes simplex infectionSRSF1B;IFNB1;BF1;IFNG;CSNK2A2A;PTPN11B;SRPK1A;SRSF6B;OAS2

HCFC2 has several biochemical functions, for example, transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HCFC2 itself. We selected most functions HCFC2 had, and list some proteins which have the same functions with HCFC2. You can find most of the proteins on our site.

Function Related Protein
transcription coactivator activityJUNBB;GMEB2;RAP2C;TDRD3;SCAND1;TFDP1B;NPAT;UTF1;RNF14

HCFC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HCFC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HCFC2.

KMT2A; MEN1; FOXO3; RBBP5; NUDCD3; SIRT1; ASH2L; ASH2L; NUDC; UTP18; capR; MYC; IRF2; PPP2R2B; ESR2; Set

Thompson-Crispi, KA; Sargolzaei, M; et al. A genome-wide association study of immune response traits in Canadian Holstein cattle. BMC GENOMICS 15:-(2014).
Tsou, YL; Lin, YW; et al. Heat Shock protein 90: Role in Enterovirus 71 Entry and Assembly and Potential Target for Therapy. PLOS ONE 8:-(2013).
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