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HCRTR1

  • Official Full Name

    hypocretin (orexin) receptor 1

  • Overview

    The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B.
  • Synonyms

    HCRTR1; hypocretin (orexin) receptor 1; orexin receptor type 1; OX1R; ox1-R; ox-1-R; orexin receptor 1; orexin receptor-1; hypocretin receptor 1; hypocretin receptor-1; hypocretin receptor type 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Bos taurus (Bovine)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian cell
  • Mammalian Cell
  • Wheat Germ
  • Yeast
  • Flag,10His
  • GST
  • His
  • His (Fc)
  • Avi
  • Flag
  • His|Myc
  • sumostar
  • N/A
  • N
  • C
  • 10×His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HCRTR1-4634H Recombinant Human HCRTR1 Protein, GST-tagged Wheat Germ GST
Human HCRTR1-4633H Recombinant Human HCRTR1 Protein Wheat Germ N/A
Human HCRTR1-5609HCL Recombinant Human HCRTR1 293 Cell Lysate HEK293 N/A
Human HCRTR1-2463H Recombinant Human HCRTR1 Protein (1-46 aa), His-Myc-tagged E.coli His/Myc 1-46 aa
Human HCRTR1-5423H Recombinant Human HCRTR1 protein, His-sumostar-tagged Yeast His-sumostar 1-46aa
Human HCRTR1-3571HF Recombinant Full Length Human HCRTR1 Protein In Vitro Cell Free System 1,210 amino acids
Human HCRTR1-12H Recombinant Human HCRTR1 Protein (M1-Q246, K288-L380), N-Flag and C-10×His-tagged Mammalian cell N-Flag and C-10×His M1-Q246, K288-L380
Human HCRTR1-3608HF Recombinant Full Length Human HCRTR1 Protein, GST-tagged In Vitro Cell Free System GST 425 amino acids
Human HCRTR1-1124HFL Recombinant Human HCRTR1 protein, His&Flag-tagged HEK293 His&Flag 1-425 aa
Human HCRTR1-0696H Recombinant Human HCRTR1 Protein (M1-Q246, K288-L380), Flag, 10×His tagged Mammalian cell Flag,10His M1-Q246, K288-L380
Human HCRTR1-294H Recombinant Human HCRTR1 Full Length Transmembrane protein(Nanodisc) HEK293 N/A
Mouse HCRTR1-7523M Recombinant Mouse HCRTR1 Protein Mammalian Cell His
Mouse HCRTR1-4085M-B Recombinant Mouse HCRTR1 Protein Pre-coupled Magnetic Beads HEK293
Mouse HCRTR1-4085M Recombinant Mouse HCRTR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat HCRTR1-2811R Recombinant Rat HCRTR1 Protein Mammalian Cell His
Rat HCRTR1-2466R-B Recombinant Rat HCRTR1 Protein Pre-coupled Magnetic Beads HEK293
Rat HCRTR1-2466R Recombinant Rat HCRTR1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bos taurus (Bovine) RFL35175BF Recombinant Full Length Bovine Orexin Receptor Type 1(Hcrtr1) Protein, His-Tagged E.coli expression system His Full Length (1-425)
Homo sapiens (Human) RFL9729HF Recombinant Full Length Human Orexin Receptor Type 1(Hcrtr1) Protein, His-Tagged E.coli expression system His Full Length (1-425)
Mus musculus (Mouse) RFL32796MF Recombinant Full Length Mouse Orexin Receptor Type 1(Hcrtr1) Protein, His-Tagged E.coli expression system His Full Length (1-416)
Rattus norvegicus (Rat) RFL29228RF Recombinant Full Length Rat Orexin Receptor Type 1(Hcrtr1) Protein, His-Tagged E.coli expression system His Full Length (1-416)
Kit-1339 HCRTR1 Total GPCR Internalization Assay Kit N/A
Kit-0915 CYP2C9 Blue Screening Kit N/A
Kit-1340 HCRTR1 CHO-K1 β-Arrestin GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein

HCRTR1 involved in several pathways and played different roles in them. We selected most pathways HCRTR1 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with HCRTR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuroactive ligand-receptor interactionGNRHR4;DRD4-RS;MC5R;HTR1B;MC1R;CHRNA10;MAS1;ADRA2DA;PTH1R

HCRTR1 has several biochemical functions, for example, G-protein coupled receptor activity, neuropeptide receptor activity, orexin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HCRTR1 itself. We selected most functions HCRTR1 had, and list some proteins which have the same functions with HCRTR1. You can find most of the proteins on our site.

Function Related Protein
G-protein coupled receptor activityFZD7;TMTOPSA;TAAR13B;LPAR5;TRHRB;GNRHR3;NMUR1;OLFCJ1;OR6B2
neuropeptide receptor activityMCHR1;SORCS1;KISS1R;KISS1RB;HCRTR1;NPFFR1;NPFFR2.1;PRLHR;SORCS3
orexin receptor activityHCRTR2;HCRTR1
peptide bindingGPR37;LTA4H;CALR;RPS6KB2;CCKAR;ERCC3;PPIB;GNRHR2;ADNP
peptide hormone bindingGCGR;PTH1RB;PTH1R;AGTR2;ANXA5;MC4R;GALR2;AGTR1A;OXTR

HCRTR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HCRTR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HCRTR1.

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