HCRTR1
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Official Full Name
hypocretin (orexin) receptor 1
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Overview
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. -
Synonyms
HCRTR1; hypocretin (orexin) receptor 1; orexin receptor type 1; OX1R; ox1-R; ox-1-R; orexin receptor 1; orexin receptor-1; hypocretin receptor 1; hypocretin receptor-1; hypocretin receptor type 1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Assay Kits
- Bos taurus (Bovine)
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian cell
- Mammalian Cell
- Wheat Germ
- Yeast
- Flag,10His
- GST
- His
- His (Fc)
- Avi
- Flag
- His|Myc
- sumostar
- N/A
- N
- C
- 10×His
- Involved Pathway
- Protein Function
- Interacting Protein
HCRTR1 involved in several pathways and played different roles in them. We selected most pathways HCRTR1 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with HCRTR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Neuroactive ligand-receptor interaction | GNRHR4;DRD4-RS;MC5R;HTR1B;MC1R;CHRNA10;MAS1;ADRA2DA;PTH1R |
HCRTR1 has several biochemical functions, for example, G-protein coupled receptor activity, neuropeptide receptor activity, orexin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HCRTR1 itself. We selected most functions HCRTR1 had, and list some proteins which have the same functions with HCRTR1. You can find most of the proteins on our site.
Function | Related Protein |
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G-protein coupled receptor activity | FZD7;TMTOPSA;TAAR13B;LPAR5;TRHRB;GNRHR3;NMUR1;OLFCJ1;OR6B2 |
neuropeptide receptor activity | MCHR1;SORCS1;KISS1R;KISS1RB;HCRTR1;NPFFR1;NPFFR2.1;PRLHR;SORCS3 |
orexin receptor activity | HCRTR2;HCRTR1 |
peptide binding | GPR37;LTA4H;CALR;RPS6KB2;CCKAR;ERCC3;PPIB;GNRHR2;ADNP |
peptide hormone binding | GCGR;PTH1RB;PTH1R;AGTR2;ANXA5;MC4R;GALR2;AGTR1A;OXTR |
HCRTR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HCRTR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HCRTR1.
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