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HEPH

  • Official Full Name

    hephaestin

  • Overview

    This gene encodes a member of the multicopper oxidase protein family. The encoded protein is involved in the transport of dietary iron from epithelial cells of the intestinal lumen into the circulatory system, and may be involved in copper transport and homeostasis. In mouse, defects in this gene can lead to severe microcytic anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
  • Synonyms

    HEPH; hephaestin; CPL;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HEPH-4689H Recombinant Human HEPH Protein, GST-tagged Wheat Germ GST
Human HEPH-5586HCL Recombinant Human HEPH 293 Cell Lysate HEK293 N/A
Human HEPH-1759H Recombinant Human HEPH Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HEPH-1596H Recombinant Human HEPH protein, His-tagged E.coli His Ala24~Cys366
Human HEPH-902HFL Recombinant Full Length Human HEPH Protein, C-Flag-tagged Mammalian cells Flag
Human HEPH-1061H Recombinant Human HEPH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human HEPH-3336H Recombinant Human HEPH Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HEPH-1061H-B Recombinant Human HEPH Protein Pre-coupled Magnetic Beads HEK293
Human HEPH-2741H Recombinant Human HEPH Protein (Ala24-Cys366), His tagged E.coli His Ala24-Cys366
Mouse HEPH-7577M Recombinant Mouse HEPH Protein Mammalian Cell His
Mouse HEPH-4125M-B Recombinant Mouse HEPH Protein Pre-coupled Magnetic Beads HEK293
Mouse Heph-1110M Recombinant Mouse Heph Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse HEPH-4125M Recombinant Mouse HEPH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat HEPH-2826R Recombinant Rat HEPH Protein Mammalian Cell His
Rat HEPH-2481R Recombinant Rat HEPH Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat HEPH-2481R-B Recombinant Rat HEPH Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

HEPH involved in several pathways and played different roles in them. We selected most pathways HEPH participated on our site, such as Porphyrin and chlorophyll metabolism, Mineral absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with HEPH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Porphyrin and chlorophyll metabolismALAS2;HCCS;FXN;UGT1A6;EPRS;FECH;UGT2B15;UROD;CPOX
Mineral absorptionSLC8A1;VDR;ATP1A1;ATP2B1;CLCN2;SLC9A3;SLC34A2;SLC46A1;SLC26A9

HEPH has several biochemical functions, for example, copper ion binding, ferrous iron binding, ferroxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HEPH itself. We selected most functions HEPH had, and list some proteins which have the same functions with HEPH. You can find most of the proteins on our site.

Function Related Protein
copper ion bindingMT1;AOC2;ABHD1;CCS;LOXL5B;HEPHL1;MT3;SCO2;S100A5
ferrous iron bindingALKBH1;TH;ISCUB;UROD;ISCA2;SERPINB1A;Trf;HAAO;ALKBH3
ferroxidase activityCP;FTMT;HEPHL1;FXN;FTH1;HEPH

HEPH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HEPH here. Most of them are supplied by our site. Hope this information will be useful for your research of HEPH.

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